Factors sustaining pediatric adherence to antiretroviral therapy in western Kenya.

Qualitative Health Research
Rachel C VreemanThomas S Inui

Abstract

Antiretroviral therapy (ART) requires nearly perfect adherence to be effective. Although 90% of HIV-infected children live in Africa, there are limited data on pediatric adherence from this multicultural continent.We conducted a qualitative study to identify key factors contributing to pediatric ART adherence. Ten focus group discussions (N = 85) and 35 individual interviews were conducted with parents and guardians of HIV-infected children receiving ART in western Kenya. Interviews covered multiple aspects of the experience of having children take ART and factors that inhibited or facilitated medication adherence. Constant comparison, progressive coding, and triangulation methods were used to arrive at a culturally contextualized, conceptual model for pediatric ART adherence derived from the descriptions of the lived experience in this resource-limited setting. Child care, including sustained ART adherence, depends on interacting cultural and environmental determinants at the levels of the individual child, parent/caregiver, household, community, health care system, and society.

References

Jan 1, 1990·Medical Care·P J Bush, R J Iannotti
Jan 1, 1988·Social Science & Medicine·R H MoosA G Billings
Mar 1, 1995·Journal of Health and Social Behavior·R M Andersen
Feb 7, 1996·American Journal of Health Promotion : AJHP·D StokolsR L Bellingham
Feb 7, 1996·American Journal of Health Promotion : AJHP·D Stokols
Dec 29, 2000·Annals of the New York Academy of Sciences·A CupsaS Dinescu
Feb 24, 2001·Behavioral Medicine·J G Grzywacz, J Fuqua
Sep 13, 2002·Journal of Medical Virology·Jane MullenPhilippa Easterbrook
Jan 25, 2003·The Pediatric Infectious Disease Journal·Diana M GibbUNKNOWN Paediatric European Network for Treatment of AIDS Steering Committee
Apr 26, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Francisco-Javier San-AndrésAngel del Palacio
May 14, 2003·American Journal of Community Psychology·Rudolf H Moos
Apr 29, 2006·The Pediatric Infectious Disease Journal·Katja DoerholtUNKNOWN Collaborative HIV Paediatric Study
Jun 23, 2006·AIDS and Behavior·Winnie Bikaako-KajuraRebecca Bunnell
Nov 14, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Winstone M NyandikoWilliam M Tierney
Nov 30, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Andrea SankarCynthia Pearson
Jun 15, 2007·Annals of Tropical Paediatrics·Nicolette Nabukeera-BarungiPhilippa Musoke
Aug 9, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kelly Safreed-HarmonJintanat Ananworanich
Aug 19, 2007·Scandinavian Journal of Infectious Diseases·Linda BracherNiels Obel
Dec 12, 2007·Cadernos de saúde pública·Neiva Isabel Raffo Wachholz, Jair Ferreira
Feb 19, 2008·The Pediatric Infectious Disease Journal·Alexandra D MüllerNicole von Steinbüchel
Jun 25, 2008·The Pediatric Infectious Disease Journal·Rachel C VreemanWinstone M Nyandiko
Sep 5, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Rachel C VreemanWinstone M Nyandiko
Mar 5, 2009·Qualitative Health Research·Patricia E Stevens, Eugenie Hildebrandt
Sep 1, 2006·African Journal of AIDS Research : AJAR·Mariya Mukhtar-YolaZubaida Farouk Ladan

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Citations

Jul 7, 2011·Journal of Public Health Policy·Jane Goudge, Bulelwa Ngoma
Dec 15, 2012·SAHARA J : Journal of Social Aspects of HIV/AIDS Research Alliance·Juddy WachiraPaula Braitstein
Mar 17, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Paula BraitsteinConstantin Yiannoutsos
Jun 21, 2013·Journal of the International AIDS Society·Annette H Sohn, Rohan Hazra
Nov 29, 2012·International Journal of Behavioral Medicine·Rachel C VreemanThomas S Inui
Jun 25, 2016·International Journal of Environmental Research and Public Health·Maria Letícia Santos CruzSimone Monteiro
Sep 23, 2016·Journal of the International Association of Providers of AIDS Care·Megan Song McHenryRachel C Vreeman
Aug 27, 2010·Qualitative Health Research·Catherine Francis Brooks
Sep 20, 2015·Journal of the International AIDS Society·Olurotimi A AdejumoBabafemi O Taiwo
Nov 28, 2014·Journal of the International AIDS Society·Rachel C VreemanThomas S Inui
Dec 6, 2014·Journal of the International AIDS Society·Kimiyo KikuchiMasamine Jimba
Oct 24, 2017·AIDS Care·Margaret W GichaneDorothy E Dow
Jun 19, 2018·Qualitative Health Research·E Ann YehUNKNOWN Pediatric MS Adherence Study Group
Jul 7, 2018·Journal of Health Communication·Juddy WachiraPaula Braitstein
Apr 16, 2019·Journal of the International AIDS Society·John M HumphreyKara Wools-Kaloustian
Oct 27, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Rachel B YoderSarah E Wiehe
Jul 10, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Carol UnderwoodElizabeth C Mallalieu
May 31, 2020·International Journal of Environmental Research and Public Health·Linda CampbellEdwin Wouters
Oct 1, 2014·Journal of HIV/AIDS & Social Services·Catherine June KunapareddyRachel Vreeman

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