PMID: 947978Jul 1, 1976Paper

Factors which influence late cutaneous allergic responses

The Journal of Allergy and Clinical Immunology
L UmemotoF E Hargreave

Abstract

Increased doses of ragweed antigen E, grass pollen extract, and the IgG of sheep antiserum to human IgE (anti-IgE) were injected in intracutaneous tests in humans. With increasing doses of reactants, in individual subjects, there were the expected increases in the sizes of early wheal-and-flare responses; moreover, there was an associated increase in the magnitude and the frequency of late cutaneous allergic responses (LCAR). LCAR were shown to be a usual sequel to allergic reactions of sufficient intensity. In persons with allergic bronchopulmonary aspergillosis, cutaneous responses to Aspergillus fumigatus allergen were compared with responses to other allergens and to anti-IgE; in relation to early wheal-and-flare responses, the corresponding LCAR induced by A. fumigatus were approximately the same size as those induced by the other reactants. Skin reactions induced by the prick test method and by intracutaneous injection were compared; for early responses of given sizes, there were apparently equal tendencies to proceed to LCAR in reactions to allergen in the two types of administration. In one subject, anti-IgE-induced responses in the skin of a forearm with sensory denervation were compared with responses in the other nor...Continue Reading

References

Feb 1, 1976·The Journal of Allergy and Clinical Immunology·J PoothullilR P Day
Jan 1, 1973·The Journal of Allergy and Clinical Immunology·S P GalantH I Maibach
Jan 1, 1972·The Journal of Allergy and Clinical Immunology·J Dolovich, D C Little
Oct 1, 1974·The Journal of Allergy and Clinical Immunology·D G RobertsonJ Dolovich
Mar 1, 1973·Clinical Allergy·J Pepys
Jan 1, 1952·International Archives of Allergy and Applied Immunology·H HERXHEIMER
Sep 1, 1958·Thorax·K M CITRONJ D SINCLAIR

Citations

Jan 1, 1988·Journal of Clinical Immunology·R F Lemanske, M A Kaliner
Jan 1, 1983·Veterinary Research Communications·A G MatthewsE A McPherson
Nov 1, 1981·The Journal of Allergy and Clinical Immunology·R L CaseP P VanArsdel
Feb 7, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·M B Lierl
Aug 7, 2001·British Journal of Pharmacology·H JonesC P Page
Jun 23, 1983·The New England Journal of Medicine·T H LeeA B Kay
May 1, 1989·The Journal of Clinical Investigation·E N CharlesworthL M Lichtenstein
Aug 1, 1992·The Journal of Clinical Investigation·R F HerrscherT J Sullivan
May 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E Henocq, J P Rihoux
Feb 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P L BruijnzeelC A Bruijnzeel-Koomen
Jun 1, 1989·The Journal of Allergy and Clinical Immunology·M E WeissN F Adkinson
Apr 1, 1985·The Journal of Allergy and Clinical Immunology·G Stålenheim, L Machado
Jul 1, 1990·The Journal of Allergy and Clinical Immunology·M ShalitB Zweiman
Jun 1, 1984·The Journal of Allergy and Clinical Immunology·K C DavisA L Schocket
Apr 1, 1989·The Journal of Allergy and Clinical Immunology·B ZimmermanM Gold
Dec 1, 1987·Immunological Investigations·R M NaclerioD Proud
Jan 1, 1987·Scandinavian Journal of Infectious Diseases. Supplementum·H Schønheyder
Mar 31, 2015·The Journal of Allergy and Clinical Immunology. in Practice·David B K Golden
Dec 1, 1991·The Journal of Allergy and Clinical Immunology·M ShalitF Levi-Schaffer
Jul 1, 1984·Clinical Allergy·L P BouletF E Hargreave
Dec 1, 1987·The British Journal of Dermatology·B M CzarnetzkiG Forck
Sep 1, 1983·International Journal of Dermatology·R F Lemanske, M A Kaliner
Sep 1, 1989·Medical Toxicology and Adverse Drug Experience·B R Lindgren, R G Andersson
Jun 11, 2016·Current Opinion in Allergy and Clinical Immunology·John Carlson, David B K Golden
Aug 1, 1990·Acta Ophthalmologica·M CalongeM R Allansmith
May 1, 1988·Current Eye Research·S D TrocméM R Allansmith
Dec 2, 1978·The Medical Journal of Australia·D Hill, B Entwisle

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