Failed tube extrusion is not a random event in children or their siblings

The Laryngoscope
Roya AzadarmakiGlenn Isaacson

Abstract

It has been assumed that prolonged retention of tympanostomy tubes was random, with an incidence of 4% to 12% per tube. We have noticed patterns of tube retention that suggested a genetic predilection. We undertook this study to validate or disprove this impression. Such information may shed light on the physiology of tube extrusion and may help better define the risks of tympanostomy tube placement. Retrospective, single-surgeon, statistical analysis. A computerized database of approximately 10,000 pediatric otolaryngology patients was queried. We identified all children treated by the senior author during a 6-year period who underwent tube removal for failed extrusion 24 or more months after placement. Siblings with retained tubes and individuals requiring bilateral tube removal were further analyzed: 1) using the law of multiplication of independent factors, the chance of retaining tubes in both ears of an individual was compared with the observed rate of bilateral retention by calculating the difference in Poisson rates; 2) the rate of siblings who retained one or both tubes was compared with nonsiblings who retained one or both tubes using the Z test for independent proportions. The observed rate of bilateral retention (22...Continue Reading

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Citations

Dec 5, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Qi ZhangThomas Kertesz
Jan 18, 2018·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Reema PadiaJeremy D Meier
Aug 28, 2020·International Journal of Pediatric Otorhinolaryngology·Mikayla J HuestisJessica R Levi
Nov 13, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery

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