Failure analysis of C-5 after total disc replacement with ProDisc-C at 1 and 2 levels and in combination with a fusion cage: finite-element and biomechanical models

Journal of Neurosurgery. Spine
António CompletoJosé Simões

Abstract

OBJECT The purpose of this study was to evaluate the failure risk of cervical vertebrae after total disc replacement with a keel-design prosthesis (ProDisc-C), taking into consideration the effects of vertebral body height, multilevel replacement, and the association with an adjacent fusion cage. Although promising clinical results have been reported for the ProDisc-C, some clinical studies have reported vertebral body-splitting fractures at single- and multilevel arthroplasty sites. This implant has central keels to provide solid initial stability, and some authors associate the potential risk of vertebral body failure with the keel design, especially in patients with small vertebral body height or when the implant is used at multiple levels. METHODS The study was performed using a specimen-specific C4-6 cervical-segment finite-element model to assess the compressive strains on the C-5 vertebral body for each cervical segment configuration, and synthetic polyurethane models to experimentally predict the compressive load at failure for 3 vertebral body heights. RESULTS The use of a keeled ProDisc-C prosthesis at multiple levels or in combination with a fusion cage increases by a factor of 2-3 the compressive strains at the C-5 ...Continue Reading

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Citations

Jun 28, 2016·The Spine Journal : Official Journal of the North American Spine Society·Cheng-Cheng YuDing-Jun Hao
Sep 24, 2016·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Elena ProvaggiDeepak M Kalaskar
Jul 19, 2018·Spine·Christoph MehrenKarin Wuertz-Kozak

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Software Mentioned

Abaqus
Catia
ScanFE
SPSS
ProDisc
ScanIP

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