Failure of a monotherapy strategy for difficult chronic prostatitis/chronic pelvic pain syndrome

The Journal of Urology
J Curtis NickelKyle Nickel

Abstract

We determined the effect of a best evidence based monotherapeutic strategy for patients diagnosed with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) referred to a specialized prostatitis clinic. Patients with CP/CPPS referred by urologists after failure of prescribed therapy for evaluation and treatment at Queen's University prostatitis research clinic were extensively evaluated, aggressively treated following a standardized treatment algorithm and followed for 1 year using a validated prostatitis specific symptom and quality of life instrument, the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). All patients underwent a standardized protocol for CP/CPPS including a history, physical examination, standard 4-glass test, plus urethral swab and semen for microscopy and culture, uroflowmetry and residual urine determination. Treatment followed a best evidence based strategy with a standardized monotherapy based algorithm. A total of 100 consecutive patients with CP/CPPS (average age 42.2 years, range 20 to 70 and average symptom duration 6.5 years, range 0.5 to 39) had 1-year followup after initial evaluation. Patients were prescribed treatment based on documentation of "failed," "successful...Continue Reading

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Citations

Dec 12, 2012·Der Urologe. Ausg. A·M WalterT M Kessler
Apr 10, 2013·World Journal of Urology·J Curtis NickelFlorian M E Wagenlehner
Jun 7, 2013·World Journal of Urology·Amin S Herati, Robert Miles Moldwin
Nov 16, 2004·Current Urology Reports·Ricardo R Gonzalez, Alexis E Te
Jun 28, 2005·Current Urology Reports·Daniel A Shoskes, Erin Katz
Jun 28, 2005·Current Urology Reports·Vi N HuaAnthony J Schaeffer
Jun 28, 2005·Current Urology Reports·Jeannette M Potts
Jul 3, 2009·Current Urology Reports·J Curtis Nickel, Daniel Shoskes
Sep 2, 2005·Clinical Evidence·Anthony Schaeffer, Thomas Jang
Feb 2, 2010·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Volkan TugcuAli Tasci
Jul 27, 2011·The Journal of Urology·Scott I Zeitlin
Dec 7, 2007·The Urologic Clinics of North America·Michel A Pontari
Oct 16, 2010·BJU International·J Curtis Nickel, Daniel A Shoskes
Feb 11, 2015·Experimental and Therapeutic Medicine·Vittorio MagriGianpaolo Perletti
Dec 14, 2011·Pain·Jeannette M Potts, Christopher K Payne
May 3, 2006·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Amir M ZiaeeMojgan Karbakhsh
Mar 15, 2006·Current Opinion in Anaesthesiology·Timothy J Ness
Sep 25, 2010·Physical Therapy·Linda S Van AlstyneEsther M Haskvitz
Jul 23, 2013·International Neurourology Journal·Jong Kyou Kwon, In Ho Chang
Dec 5, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Giuseppe PennaLuciano Adorini
Jun 6, 2013·Experimental and Therapeutic Medicine·Zhongming Sun, Yanzhong Bao
Jun 24, 2010·Expert Opinion on Pharmacotherapy·Devon C Snow, Daniel A Shoskes

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