Failure of fear extinction in insomnia: An evolutionary perspective.

Sleep Medicine Reviews
Lampros PerogamvrosThien Thanh Dang-Vu

Abstract

The pathophysiology of insomnia remains poorly understood, yet emerging cross-disciplinary approaches integrating natural history, observational studies in traditional populations, gene-phenotype expression and experiments are opening up new avenues to investigate the evolutionary origins of sleep disorders, with the potential to inform innovations in treatment. Previous authors have supported that acute insomnia is a normal biopsychosocial response to a perceived or real threat and may thus represent an adaptive response to stress. We further extend this hypothesis by claiming that insomnia reflects a fear-related evolutionary survival mechanism, which becomes persistent in some vulnerable individuals due to failure of the fear extinction function. Possible treatments targeting fear extinction are proposed, such as pharmacotherapy and emotion-based cognitive behavioral therapy.

References

May 1, 1986·Electroencephalography and Clinical Neurophysiology·R R Freedman
Jan 1, 1967·Psychophysiology·B K LesterR C Dossett
Nov 14, 1997·Journal of Sleep Research·M L PerlisJ K Wyatt
Oct 17, 1998·Psychosomatic Medicine·M H Bonnet, D L Arand
Sep 1, 1994·Journal of Sleep Research·J E Broman, J Hetta
Jun 9, 2000·Annual Review of Neuroscience·W Schultz, A Dickinson
Apr 20, 2001·JAMA : the Journal of the American Medical Association·J D EdingerR E Quillian
Aug 15, 2001·The Journal of Clinical Endocrinology and Metabolism·A N VgontzasG P Chrousos
Aug 25, 2001·Annual Review of Neuroscience·S Maren
Sep 19, 2001·Sleep·D A SuttonE M Badley
Aug 21, 2002·Behaviour Research and Therapy·A G Harvey
Oct 29, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S ScholleG Zwacka
Jan 13, 2004·The Journal of Clinical Endocrinology and Metabolism·Dieter KunzFrederik Bes
Jan 30, 2004·Psychosomatic Medicine·Martica HallJulian F Thayer
Oct 30, 2004·The American Journal of Psychiatry·Eric A NofzingerDavid J Kupfer
Oct 29, 2005·The Journal of Comparative Neurology·Clifford B SaperThomas E Scammell
Dec 13, 2006·Molecular Psychiatry·K M Myers, M Davis
Apr 18, 2007·Pediatrics·Dominique PetitJacques Montplaisir
Aug 30, 2007·Nature Neuroscience·Andreas Olsson, Elizabeth A Phelps
Sep 21, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Gregory J Quirk, Devin Mueller
Oct 17, 2007·Behavioral Sleep Medicine·Eui-Joong Kim, Joel E Dimsdale
Nov 17, 2007·Behaviour Research and Therapy·Michelle G CraskeAaron Baker
Apr 12, 2008·Sleep Medicine Reviews·John A LeskuSteven L Lima
Oct 3, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Georgina CanoClifford B Saper
Mar 11, 2009·Archives of Internal Medicine·Charles M MorinJean-Pierre Grégoire
Jun 2, 2009·Sleep Medicine Reviews·Dieter RiemannChristoph Nissen
Jul 25, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Lisa M Shin, Israel Liberzon
Jul 31, 2009·Sleep Medicine Reviews·Michael H Bonnet, Donna L Arand
Sep 4, 2009·Sleep·Mélanie LeBlancCharles M Morin
Sep 21, 2010·Journal of Clinical Psychology·Wilfred R Pigeon
Dec 22, 2010·Neuron·Clifford B SaperThomas E Scammell
Jan 22, 2011·Neuroscience and Biobehavioral Reviews·Mark V FlinnDavide Ponzi
Apr 5, 2011·European Journal of Radiology·Zhaoyang HuangKuncheng Li
May 21, 2011·Sleep Medicine Reviews·Jason G EllisMichael L Perlis
Jul 2, 2011·NeuroImage·Lino NobiliFabrizio De Carli
Aug 26, 2011·The American Journal of Psychiatry·Bronwyn M Graham, Mohammed R Milad
Nov 15, 2011·Drug Discovery Today. Disease Models·Daniel J BuysseEric A Nofzinger
Dec 2, 2011·Annual Review of Psychology·Mohammed R Milad, Gregory J Quirk
Jan 31, 2012·American Journal of Human Biology : the Official Journal of the Human Biology Council·Michael L Power

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Trained Nurse and Hospital Review
D G SPICER
British Medical Journal
E B STRAUSS
JAAPA : Official Journal of the American Academy of Physician Assistants
Nursing
M Jahanshahi
The New England Journal of Medicine
P SOLOMON
© 2021 Meta ULC. All rights reserved