Failure of intravascular ultrasound to predict dissection after balloon angioplasty by using plaque characteristics

American Heart Journal
A van der LugtH Pieterman

Abstract

Intravascular ultrasound (IVUS) is more sensitive than angiography in the assessment of plaque characteristics before intervention and vascular damage after balloon angioplasty. On the basis of IVUS data, this finding may improve clinical treatment by reducing the incidence of severe dissections after balloon angioplasty. We therefore studied the relation between plaque characteristics and dissections after balloon angioplasty. First, an in vitro study on atherosclerotic arteries (n = 42) was performed in which IVUS images were compared with histologic sections to validate the IVUS technique; second, the in vitro findings were compared with IVUS findings obtained in vivo (n = 73). Dissections were observed in 37 histologic sections and visualized on IVUS in 22 (59%) of the corresponding ultrasonic cross-sections; in vivo dissections were demonstrated by IVUS in 46 (63%) cases. Dissections were generally seen at the thinnest region of the plaque on both histologic sections (92%) and IVUS cross-sections (in vitro 83%; in vivo 93%). No significant relation was found between pre-interventional plaque characteristics such as composition features and eccentricity and the incidence, location, and extent of postinterventional dissectio...Continue Reading

References

Nov 15, 1992·Journal of the American College of Cardiology·A N TenagliaC J Davidson
Sep 1, 1992·Journal of the American College of Cardiology·A N TenagliaC J Davidson
Oct 1, 1992·Journal of the American College of Cardiology·B N PotkinM B Leon
Jan 1, 1991·International Journal of Cardiac Imaging·L WenguangH van Urk
Nov 15, 1991·The American Journal of Cardiology·C J DavidsonJ E Tcheng
Nov 1, 1990·Journal of the American College of Cardiology·A FarbF D Kolodgie
Oct 1, 1989·Journal of the American College of Cardiology·E J GussenhovenJ Roelandt
May 1, 1987·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·R T LyonS Glagov
Sep 1, 1984·International Journal of Cardiology·J M Isner, D N Salem
Aug 13, 1981·The New England Journal of Medicine·P C BlockJ T Fallon
Jan 1, 1994·Ultrasound in Medicine & Biology·L S WilsonM Appleberg

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