Failure of introduction of food allergens after negative oral food challenge tests in children

European Journal of Pediatrics
J P M van der ValkN W de Jong

Abstract

One of the purposes to perform an oral food challenge (FC) test is to avoid unnecessary elimination of food allergens. In case of a negative FC test result, the food can be introduced. It is, however, unknown if patients act according to the outcome of the test. This study evaluates the rate of introduction of peanut, hazelnut, cow's milk or hen's egg allergens after a negative FC test. We investigated the introduction rate of children (0-18 years) with a negative FC test visiting the Department of Allergology, Erasmus Medical Centre Rotterdam from 2008 till 2013 and the factors that influence the rate of introduction. Patients were asked to complete a comprehensive questionnaire about their FC test. In total, 157 (38% girls, mean age during challenge 6.9 years) participated in the study. Of these FC tests, 104 (56%) were followed by a successful introduction, 30 (16%) by a partly introduction (traces or processed foods) and 52 (28%) by a failed introduction. Peanut and hazelnut showed a statistically significant lower successful introduction rate. Age, gender, symptoms during FC test, dietary advice and time period to introduction significantly influenced the rate of introduction. One fourth of the children with failure of int...Continue Reading

References

Nov 24, 2006·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Philippe A EigenmannSamuel A Zamora
Feb 20, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T F LeungG W K Wong
May 16, 2009·Current Opinion in Allergy and Clinical Immunology·Anna Nowak-Wegrzyn, Alessandro Fiocchi
Oct 3, 2009·Allergy·Bodo Niggemann
Apr 24, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N W de JongR Gerth van Wijk
Sep 10, 2014·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Francine C van ErpYolanda Meijer

❮ Previous
Next ❯

Citations

Feb 26, 2016·Clinical and Translational Allergy·J P M van der ValkN W de Jong
May 5, 2016·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·J P M van der ValkN W de Jong
Aug 9, 2016·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·J P M van der ValkN W de Jong
May 28, 2019·European Journal of Pediatrics·Michael SchrijversImke Annelieke Bertrams-Maartens
Jan 20, 2020·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Astrid VersluisHarmieke van Os-Medendorp
Nov 1, 2018·Current Allergy and Asthma Reports·Amanda L Cox, Anna Nowak-Wegrzyn
Sep 15, 2021·Clinical Reviews in Allergy & Immunology·Ling-Jen WangCheng-Hui Lin
Oct 22, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jamie Wei Min Cheah, Brynn Kevin Wainstein

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
Zein Faraj, Harold L Kim
The Journal of Allergy and Clinical Immunology
Kim MuddRobert Wood
Archivum Immunologiae Et Therapiae Experimentalis
Susana R M PassetiNeusa F Wandalsen
© 2021 Meta ULC. All rights reserved