PMID: 39308Jun 21, 1979

Failure of MIF-I to affect behavioral responses in patients with Parkinson's diseases under L-dopa therapy

T A CaraceniE E Müller


In eight subjects with Parkinson's disease under an optimal daily dose of L-dopa, acute administration of MIF-I (200 mg i.v.) did not ameliorate either the total disability score or the intellectual test PM 38 when evaluated in comparison with the effect induced by acute administration of a placebo. Also concomitant evaluation of the effect of MIF-I on the secretion of anterior pituitary hormones which are under dopaminergic control i.e., growth hormone and prolactin, did not reveal any potentiation of the L-dopa-induced stimulus.


Jan 1, 1976·Pharmacology, Biochemistry, and Behavior·R M KostrzewaT H Joh
Jan 1, 1976·Pharmacology, Biochemistry, and Behavior·T J Crowley, M Hydinger
Sep 1, 1978·Pharmacology, Biochemistry, and Behavior·R M KostrzewaS K Sobrian
Dec 1, 1977·Journal of Neurology, Neurosurgery, and Psychiatry·T A CaraceniF Girotti
Aug 1, 1976·Neuropharmacology·M RezekH Friesen
Jul 1, 1974·Archives of Neurology·T N ChaseC E Morris
Jan 1, 1973·Neuroendocrinology·N P PlotnikoffA V Schally
Nov 15, 1971·Life Sciences. Pt. 1: Physiology and Pharmacology·N P PlotnikoffA V Schally
Jul 1, 1972·Proceedings of the Society for Experimental Biology and Medicine·N P PlotnikoffA V Schally
Jul 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·M E CelisR Walter

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MSH Release-Inhibiting Hormone
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