PMID: 653534Feb 25, 1978Paper

Failure of pyridoxine to suppress raised serum prolactin levels

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
J M de WaalP R Pannall

Abstract

Pyridoxine has been reported as having an antilactogenic effect, presumably by suppressing prolactin secretion. We have measured serum prolactin levels during pyridoxine administration in two groups of hyperprolactinaemic subjects. In normal postpartum women, the postdelivery fall in serum prolactin levels did not differ significantly in treated and control subjects. In patients with chlorpromazine-induced hyperprolactinaemia and galactorrhoea, pyridoxine did not reduce the elevated levels. In neither group was milk production suppressed.

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