Fallopian tube sperm perfusion has no advantage over intra-uterine insemination when used in combination with ovarian stimulation for the treatment of unexplained infertility

Gynecologic and Obstetric Investigation
O GregoriouP A Zourlas


In this prospective randomized study we treated 60 couples with unexplained infertility with a combination of ovarian stimulation and either intrauterine insemination (IUI) or fallopian sperm perfusion (FSP). In the IUI we used a volume of 0.5 ml of inseminate and in the FSP a volume of 4 ml. The demographic characteristics of the patients, the stimulation parameters and the sperm data were not statistically different between the two groups. The pregnancy rate per cycle was 16.2% in the IUI group and 14.5% in the FSP group and the pregnancy rate per woman was 40 and 36.7%, respectively (not statistically different). We conclude that IUI and FSP are equally effective in the treatment of couples with unexplained infertility.


Oct 27, 2004·Gynécologie, obstétrique & fertilité·T Forges, P Monnier-Barbarino
Feb 24, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Waleed El-KhayatAly Moafy
Nov 1, 2013·The Cochrane Database of Systematic Reviews·Astrid E P CantineauCindy Farquhar
Mar 22, 2019·Human Reproduction Open·Jorge Rodriguez-PurataBuenaventura Coroleu

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