Falls and fall-related injury are common in older people with chronic liver disease.

Digestive Diseases and Sciences
James FrithJulia L Newton

Abstract

Improved survival with chronic liver disease (CLD) and increased incidence in the older has led to a rapidly expanding population which faces similar "geriatric syndromes" as the general population. With risk factors such as autonomic dysfunction, cognitive impairment, and muscle abnormalities in CLD it is expected that falls and injury will be common. To determine prevalence of falls and injury in chronic liver disease and to identify potential modifiable fall associations. Falls prevalence was estimated by providing patients aged ≥ 65 years with CLD a falls data collection tool, via the post or in the clinic. A younger CLD cohort and age-matched and sex-matched community controls was used for comparison. A sub-group underwent multidisciplinary falls assessment to identify modifiable fall associations. Falls were significantly more common in older people with CLD (47 % in previous year) than in controls; incidence of injury did not differ. Regression identified orthostatic symptoms, lower-limb strength, and fear of falling as being independently associated with falls in CLD. Those who had fallen had significantly greater difficulty with daily activities. Falls are prevalent in older people with CLD, and are potentially prevent...Continue Reading

References

Feb 1, 1986·Journal of the American Geriatrics Society·M E Tinetti
Apr 1, 1997·QJM : Monthly Journal of the Association of Physicians·D R Parker, J G Kingham
Jul 4, 2001·Gastroenterology Clinics of North America·A Regev, E R Schiff
Sep 26, 2002·Journal of the Royal Statistical Society. Series A, (Statistics in Society)·D BlaneM Rosato
Jul 11, 2003·Lancet·Jayant A Talwalkar, Keith D Lindor
Oct 19, 2004·European Journal of Gastroenterology & Hepatology·Dominique PessayreAbdellah Mansouri
Mar 11, 2005·Mayo Clinic Proceedings·Christine SchrezenmaierPaola Sandroni
Sep 3, 2005·Journal of the American Geriatrics Society·Sarah E LambUNKNOWN Prevention of Falls Network Europe and Outcomes Consensus Group
Mar 2, 2006·European Journal of Anaesthesiology·F LhuillierJ P Viale
Oct 17, 2006·Worldviews on Evidence-based Nursing·Liz McInnesJacqueline Chandler-Oatts
Feb 3, 2007·European Journal of Gastroenterology & Hepatology·Julia L NewtonDavid E J Jones
Jun 20, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Julia L NewtonDavid Jones
Aug 12, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Kieren G HollingsworthDavid E J Jones
Mar 28, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·James Frith, Julia L Newton
Jan 4, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Germán SorianoCarlos Guarner

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Citations

Jan 27, 2017·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Meric Yildirim
Oct 18, 2018·Digestive Diseases and Sciences·Susan L MurphyJames K Richardson
May 7, 2019·World Journal of Gastroenterology : WJG·Kenya KamimuraShuji Terai
Jan 20, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J Powell, A Michael
Nov 27, 2019·The Journal of Surgical Research·Kartik PrabhakaranRifat Latifi

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