Falls and risk factors for falls in community-dwelling adults with dementia (NutriAlz trial)

Alzheimer Disease and Associated Disorders
A SalvàBruno Vellas

Abstract

To estimate the number of fallers and risk factors for falls in a cohort with dementia, we did a secondary analysis of a cluster-randomized controlled trial (NutriAlz) in 11 outpatient and day care centers in Catalonia (Spain) including 626 community-dwelling patients with dementia, followed for 12 months. Participants' characteristics were assessed at baseline, at 6 and 12 months [fall in the earlier 6 mo, anthropometric data, comorbidities, Mini-Mental State Examination, Clinical Dementia Rating, Basic Activities of Daily Living (BADL), Instrumental Activities of Daily Living, Neuropsychiatric Inventory Questionnaire, Zarit Caregiver Burden Interview and Mini-Nutritional Assessment]. Multivariate logistic regression models and generalized linear models were used to explore risk factors for falls and changes in health and function. Two hundred twenty-three participants fell during the 12 months follow-up (35.62%). Risk factors identified for falls were age (odds ratio (OR)=1.03, 95% confidence interval (CI), 1.00-1.05), BADL (OR=1.18, 95% CI, 1.05-1.32), and earlier fall (OR=2.30, 95% CI, 1.57-3.35). Fallers had worse health than nonfallers, and their dependence increased significantly more in BADL during the study, compared w...Continue Reading

Associated Clinical Trials

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jun 1, 1991·American Journal of Epidemiology·A H MyersE G Robinson
Dec 29, 1988·The New England Journal of Medicine·M E TinettiS F Ginter
Feb 1, 1988·Biological Psychiatry·G S AlexopoulosC A Shamoian
Jul 1, 1987·Journal of Gerontology·J C MorrisS A Mandel
Jun 1, 1986·The Gerontologist·S H ZaritJ M Zarit
Sep 23, 2000·The Journal of Neuropsychiatry and Clinical Neurosciences·D I KauferS T DeKosky
Aug 6, 2002·Neurologia Medico-chirurgica·Tsutomu TokuyamaHiroki Namba
Sep 13, 2003·Health Services Research·Sebastian SchneeweissRobert J Glynn
Sep 21, 1963·JAMA : the Journal of the American Medical Association·S KATZM W JAFFE
Aug 12, 2005·Internal Medicine·Etsuo HorikawaHidetada Sasaki
Oct 14, 2006·Journal of the American Geriatrics Society·Carolyn W ZhuYaakov Stern
Feb 17, 2007·Journal of the American Geriatrics Society·Yves RollandBruno Vellas
Sep 27, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Maud J L GraffMarcel G M Olderikkert
Mar 18, 2009·Journal of Advanced Nursing·Jürgen HärleinCornelia Heinze
Jun 19, 2009·The Journal of Nutrition, Health & Aging·A SalvaUNKNOWN NutriAlz Group

❮ Previous
Next ❯

Citations

Jul 27, 2012·International Psychogeriatrics·Morag E TaylorJacqueline C T Close
Oct 24, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Morag E TaylorJacqueline C T Close
Feb 26, 2016·Revista española de geriatría y gerontología·Marco InzitariNicolás Martínez
Aug 8, 2014·Journal of Peptide Science : an Official Publication of the European Peptide Society·Tamás Vajda, András Perczel
Nov 15, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Alan C Tsai, Mei-Yen Lai
Jul 6, 2014·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Sheila de Melo BorgesOrestes Vicente Forlenza
Aug 29, 2018·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·Jindong Ding PetersenFrans Boch Waldorff
Aug 9, 2017·Journal of Geriatric Physical Therapy·Juliana Hotta AnsaiJosé Rubens Rebelatto
Jul 12, 2017·Dementia and Geriatric Cognitive Disorders Extra·Niko M PerttilaKaisu H Pitkala

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Current Opinion in Clinical Nutrition and Metabolic Care
Emanuele Cereda
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
L Z RubensteinBruno Vellas
The Journal of Nutrition, Health & Aging
E IsenringG Kerr
© 2022 Meta ULC. All rights reserved