False-Positive PET/CT After Cyanoacrylate Sealing of a Pancreaticojejunostomy

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Orlin BelyaevWaldemar Uhl

Abstract

In 2013, a 68-year-old male had a pancreaticoduodenectomy for pancreatic cancer. The pancreaticojejunostomy was sealed with cyanoacrylate (Dermabond) to prevent postoperative pancreatic fistula. Local recurrence of malignancy at the anastomosis was suspected 18 months later in PET/CT. Surgical revision was performed and anastomosis resected. However, histology showed no tumor recurrence, but strong inflammation and foreign-body reaction towards Dermabond. The sealant caused false-positive PET/CT findings, so its use in oncologic surgery should be abandoned.

References

May 15, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Omar BarakatR Patrick Wood
Feb 7, 2013·The Journal of Surgical Research·Konstantinos A VakalopoulosJohan F Lange

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Citations

Dec 5, 2017·Abdominal Radiology·S JavadiE P Tamm
Jan 17, 2017·World Journal of Surgery·Laura-Christin TillmannOrlin Belyaev
May 30, 2021·Seminars in Nuclear Medicine·Esra Arslan, Tevfik Fikret Çermik

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