False rise of starch-iodine determined amylase values caused by heparin treatment during haemodialysis.

Clinica Chimica Acta; International Journal of Clinical Chemistry
A Pasternack, U H Stenman

Abstract

A false rise in the levels of serum amylase as determined by a starch-iodine method was observed in patients undergoing haemodialysis and after treatment with heparin. In in vitro experiments, neither dialysis of serum nor addition of heparin produced a corresponding increase. The results showed that lipoproteins, altered by heparin-induced lipoprotein lipase, may have a considerable influence by interacting with starch and thereby partly preventing the formation of starch-iodine complexes. Amyloclastic methods that employ the starch-iodine reaction for determining amylase are therefore not to be used on patients treated with heparin.

References

Feb 13, 1971·Lancet·H O Collier
Feb 13, 1971·Lancet·A Pasternack
May 15, 1969·Experientia·M CeskaB G Ingelman
Sep 1, 1955·The Journal of Clinical Investigation·R J HAVELJ H BRAGDON
Jul 1, 1959·American Journal of Clinical Pathology·W T CARAWAY
Nov 1, 1963·Clinica Chimica Acta; International Journal of Clinical Chemistry·P WILDING

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Citations

Mar 14, 1983·Clinica Chimica Acta; International Journal of Clinical Chemistry·A PasternackJ Helenius

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