Familial isolated pituitary adenomas (FIPA) and mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene

Endocrinology and Metabolism Clinics of North America
Adrian Daly, Albert Beckers

Abstract

The most frequent conditions that are associated with inherited/familial pituitary adenomas are familial isolated pituitary adenoma (FIPA) and multiple endocrine neoplasia type 1 (MEN1), which together account for up to 5% of pituitary adenomas. One important genetic cause of FIPA are inactivating mutations or deletions in the aryl hydrocarbon receptor interacting protein (AIP) gene. FIPA is the most frequent clinical presentation of AIP mutations. This article traces the current state of knowledge regarding the clinical features of FIPA and the particular genetic, pathologic, and clinical characteristics of pituitary adenomas due to AIP mutations.

References

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Sep 14, 2006·The Journal of Clinical Endocrinology and Metabolism·Adrian F DalyAlbert Beckers
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Citations

Dec 17, 2015·Endocrine-related Cancer·Adrian F DalyAlbert Beckers
Mar 5, 2016·Endocrine-related Cancer·Adrian F DalyAlbert Beckers
Dec 17, 2016·Endocrine·Adrian F Daly, Albert Beckers
Oct 27, 2018·Nature Reviews. Endocrinology·Albert BeckersAdrian F Daly
Dec 22, 2017·Journal of the Endocrine Society·Mary P GillamEun Jig Lee
Jan 31, 2020·The Journal of Clinical Endocrinology and Metabolism·Pedro MarquesUNKNOWN FIPA Consortium
Feb 6, 2017·Pituitary·Mônica R GadelhaMárta Korbonits
Apr 4, 2021·Journal of Clinical Medicine·Anna Bogusławska, Márta Korbonits
Feb 8, 2019·Neuroendocrinology·Laurent VroonenAlbert Beckers

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