Familial Liability for Eating Disorders and Suicide Attempts: Evidence From a Population Registry in Sweden

JAMA Psychiatry
Shuyang YaoCynthia M Bulik

Abstract

Suicide attempts are common in individuals with eating disorders. More precise understanding of the mechanisms underlying their concomitant occurrence is needed. To examine the association between eating disorders and suicide attempts and whether familial risk factors contribute to the association. A Swedish birth cohort including individuals born in Sweden between January 1, 1979, and December 31, 2001, was followed up from age 6 years to December 31, 2009 (N = 2,268,786). Information was acquired from Swedish national registers. All individuals were linked to their biological full siblings, maternal half siblings, paternal half siblings, full cousins, and half cousins. Data analysis was conducted from October 5, 2014, to April 28, 2015. Eating disorders were captured by 3 variables (any eating disorder, anorexia nervosa, and bulimia nervosa) identified by any lifetime diagnoses recorded in the registers. Suicide attempts were defined as any suicide attempts, including death by suicide, recorded in the registers. We examined the association between eating disorders and death by suicide separately, but the study was underpowered to explore familial liability for this association. Of 2,268,786 individuals, 15,457 females (1.40% ...Continue Reading

Citations

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