PMID: 7082025May 1, 1982Paper

Familial vulvar dystrophy of lichen sclerosus type

Archives of Dermatology
F R MurphyH F Haberman


Lichen sclerosus et atrophicus (LS&A) of the vulva and perianal skin is an atrophic condition that con occur alone or in association with additional lesions situated elsewhere on the skin surface. The cases of three sisters with LS&A of the vulva are reported herein; in one a squamous cell carcinoma developed in a hyperplastic area of mixed dystrophy (LS&A with foci of hyperplasia). Familial occurrences of LS&A are rare. Malignant neoplasms arising in areas of LS&A have been reported previously. Squamous cell carcinoma arises in hyperplastic areas of mixed dystrophy where there is evidence of both LS&A and epithelial hyperplasia.


Nov 16, 2005·Clinical Obstetrics and Gynecology·Isabel Val, Gutemberg Almeida
Feb 9, 2005·Annales de dermatologie et de vénéréologie·L Labbé, C Léauté-Labrèze
Mar 6, 2010·Journal of the European Academy of Dermatology and Venereology : JEADV·V ShermanF Wojnarowska

Related Concepts

Anal Canal
Squamous Cell Carcinoma
Vulvar Lichen Sclerosus
Dermatologic Disorders
Malignant Neoplasm of Vulva

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Carcinoma, Squamous Cell

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