PMID: 9439061Jan 24, 1998Paper

Family correlations of metacarpal bones--heritable (h2) and environmental (c2) components of total phenotypic variation

Collegium antropologicum
Tatjana Skarić-Jurić, P Rudan

Abstract

The analysis of family data of 18 metacarpal morphometric dimensions (bone length -L, total diaphysis width-T and medullary canal width-M of the second, third and fourth metacarpals of both hands) has been performed on 956 randomly sampled adult examinees (age 18 to 85), inhabitants of the islands of Brac and Hvar and the Peljesac peninsula, Croatia. Interclass (for parent-offspring family pairs) and intraclass (for siblings) correlation coefficients have been calculated as well as heritability coefficient (h2) and coefficient quantifying effects of common sibling environment (c2) have been estimated. Heritability estimates (h2) for the medullary canal width dimensions (54%-71%) showed to be at least as high, and c2 (2%-14%) values showed to be at least as low as those obtained for bone length dimensions (h2 = 51%-65%; c2 = 5%-16%) suggesting a strong influence of genetic factors in medullary canal width formation. For both traits the highest heritability and the lowest environmental component is found for dimensions of 4th metacarpal bone, which could be explained by lower biomechanical pressures acting on that bone owing to it's anatomical position. Analysis of family resemblance for medullary canal width showed the tendency ...Continue Reading

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