Family history and risk of breast cancer: nurses' health study.

Breast Cancer Research and Treatment
Graham A ColditzBernard Rosner

Abstract

Family history of cancer remains underused in general clinical practice. We assess age at diagnosis and the role of family history in risk of breast cancer. Prospective follow-up of nurses' health study participants from 1980 to 2006. Updated assessment of family history in mother and sister including age at diagnosis. We used youngest age at diagnosis for family member when classifying risk. We confirmed 4327 incident invasive breast cancers confirmed. Breast cancer incidence models fitted to women with and without family history to assess variation in the risk for established risk factors. Compared to women with no family history those whose mother was diagnosed before age 50 had an adjusted relative risk of 1.69 (95% CI 1.39-2.05) and those with mother diagnosed at 50 or older had a relative risk of 1.37 (1.22-1.53). Sister history was associated with increased relative risk; 1.66 (1.38-1.99) for those with sister history before age 50 and 1.52 (1.29-1.77) for those with sister diagnosed at age 50 or older. Women with either mother or sister diagnosed before age 50 had a relative risk of 1.70 (1.48-1.95) significantly higher than those with diagnosis at age 50 or older (RR = 1.30; (1.27-1.54), P = 0.016). The magnitude of ri...Continue Reading

References

Jul 1, 1990·Epidemiology·B FloderusT M Mack
Jul 21, 1993·JAMA : the Journal of the American Medical Association·G A ColditzB A Rosner
May 15, 2002·The American Journal of Gastroenterology·Paul C SchroyAdam C Geller
Jun 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Donald A BerryGiovanni Parmigiani
Sep 3, 2002·Annals of Internal Medicine·UNKNOWN U.S. Preventive Services Task Force
Mar 20, 2003·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Sandy Suther, Patricia Goodson
Jun 6, 2003·The New England Journal of Medicine·Richard Wooster, Barbara L Weber
Sep 24, 2004·JAMA : the Journal of the American Medical Association·Harvey J MurffSapna Syngal
Nov 27, 2004·The New England Journal of Medicine·Alan E GuttmacherRichard H Carmona
May 3, 2005·Nature Reviews. Cancer·Graham A Colditz, Susan E Hankinson
Jul 13, 2006·JAMA : the Journal of the American Medical Association·A Heather EliassenSusan E Hankinson
Jan 15, 2009·Journal of the National Cancer Institute·Timothy R RebbeckSusan M Domchek
Oct 30, 2009·Public Health Genomics·K Dunlop, K Barlow-Stewart
Nov 19, 2009·Annals of Internal Medicine·UNKNOWN US Preventive Services Task Force
Jun 23, 2010·The Medical Journal of Australia·Jon D EmeryDavid Ravine
May 13, 2011·Journal of the National Cancer Institute·Rachel A Freedman, Judy E Garber
May 13, 2011·Journal of the National Cancer Institute·Phuong L MaiLouise Wideroff
Jul 28, 2011·Journal of the National Cancer Institute·Daniele CampaFederico Canzian

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Citations

May 9, 2014·Cancer Causes & Control : CCC·Louise A BrintonCher M Dallal
Aug 12, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Ruhi KapahiNeeti Rajan Singh
Feb 3, 2015·Psycho-oncology·Cathleen D ZickKen R Smith
Jan 28, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Yi-Xia ZhangJing Geng
Nov 15, 2014·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Beth A ConlonAlyson Moadel-Robblee
Apr 14, 2016·Journal of Cancer Research and Therapeutics·Ranen Kanti AichJibak Bhattacharaya
Dec 18, 2014·Archives of Gynecology and Obstetrics·Fabienne Dominique SchwabUwe Güth
Nov 1, 2013·Epigenetics : Official Journal of the DNA Methylation Society·Lissette Delgado-CruzataMary Beth Terry
Dec 17, 2014·Current Opinion in Obstetrics & Gynecology·Melanie Wuttke, Kelly-Anne Phillips
Aug 29, 2012·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Arnaldo C CoutoUNKNOWN Brazilian Collaborative Study Group of Infant Acute Leukemia
Aug 13, 2014·World Journal of Clinical Oncology·Rupen ShahS David Nathanson
Nov 2, 2017·AJR. American Journal of Roentgenology·Colleen H NealMark A Helvie
Jun 12, 2018·Nigerian Journal of Clinical Practice·U R EbubedikeS N C Anyanwu
Jun 5, 2017·Breast Cancer Research and Treatment·Hannah R BrewerAnthony J Swerdlow
Jul 19, 2017·Molecular Genetics & Genomic Medicine·Alison Johnston, Michael Sugrue
Nov 18, 2016·The Medical Journal of Australia·Ian N Olver
May 28, 2020·Obstetrics and Gynecology·David ChelmowJulia Sage O'Hara
Oct 8, 2017·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Oyewale O ShiyanbolaAmy Trentham-Dietz
Sep 15, 2017·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Lynn Chollet-HintonMelissa A Troester
Apr 25, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Robert J GlynnBernard Rosner
Jan 2, 2016·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Traci N BetheaJulie R Palmer
Jan 13, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Harshini MallipeddiRavi P Sahu

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