Family history and risk of hospital treatment for varicose veins in Sweden

The British Journal of Surgery
B ZöllerKristina Sundquist

Abstract

Family history has been suggested as a risk factor for varicose veins, but recall bias may inflate the familial risks. The aim of this nationwide study was to determine familial risks for hospital treatment for varicose veins. Data from the Swedish Multi-Generation Register of people aged 0-76 years were linked to Hospital Discharge Register data for 1964-2008. Standardized incidence ratios (SIRs) were calculated for individuals whose relatives were treated in hospital for varicose veins and compared with those whose relatives were not. Only main diagnoses of varicose veins were considered. A total of 39 396 people had hospital treatment for varicose veins. The familial SIR among offspring with one affected parent was 2·39 (95 per cent confidence interval 2·32 to 2·46). The SIR for those with one affected sibling was 2·86 (2·76 to 2·97). SIRs were increased in both men and women. The SIR for individuals with two or more affected siblings or with two affected parents was 5·88 (5·28 to 6·53) and 5·52 (4·77 to 6·36) respectively. The SIR for the wives of men treated for varicose veins was 1·69 (1·59 to 1·80); that for the husbands of women treated for varicose veins was 1·68 (1·58 to 1·79). Using the Swedish Hospital Discharge Reg...Continue Reading

References

Aug 1, 1969·British Journal of Preventive & Social Medicine·J M Weddell
Jan 1, 1994·Gerontology·B KomsuoğluS S Komsuoğlu
May 1, 1994·The Journal of Dermatologic Surgery and Oncology·A Cornu-ThenardP H Carpentier
Feb 13, 2001·British Journal of Cancer·K HemminkiD Easton
Jun 8, 2002·World Journal of Surgery·Jari O LaurikkaMatti Hakama
Mar 26, 2003·Journal of Clinical Epidemiology·Amanda J LeeF Gerald R Fowkes
Nov 27, 2004·The New England Journal of Medicine·Alan E GuttmacherRichard H Carmona
Jun 3, 2006·Stroke; a Journal of Cerebral Circulation·Kristina SundquistKari Hemminki
Aug 5, 2006·BMJ : British Medical Journal·Bruce Campbell
Oct 3, 2006·Carcinogenesis·Kari Hemminki, Justo Lorenzo Bermejo
Mar 21, 2007·Circulation·Russell H MellorUNKNOWN Lymphoedema Research Consortium
Oct 23, 2009·The British Journal of Surgery·C S Lim, A H Davies
Nov 12, 2009·Diabetes Care·Kari HemminkiJan Sundquist
Jan 9, 2010·Journal of Clinical Epidemiology·Tiina M AhtiJari O Laurikka
Jun 11, 2011·BMC Public Health·Jonas F LudvigssonPetra Otterblad Olausson

❮ Previous
Next ❯

Citations

Nov 14, 2013·American Journal of Epidemiology·Morten ValbergOdd O Aalen
Oct 10, 2014·The Journal of Dermatology·Kunie KohnoKuninori Shiwaku
Oct 11, 2014·International Journal of Vascular Medicine·Nazmiye Selçuk KapısızHasan Fahri Kapısız
Apr 30, 2015·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C WittensUNKNOWN European Society for Vascular Surgery
Jun 28, 2016·Journal of the American College of Surgeons·Kunie KohnoBengt Zöller
Sep 18, 2016·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Elizabeth A AndraskaDawn M Coleman
Jan 21, 2016·Phlebology·Yasmin GrantAlun Davies
May 10, 2017·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Bettina Santler, Tobias Goerge
May 10, 2017·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Bettina Santler, Tobias Goerge
Aug 22, 2018·Biomarkers in Medicine·Raffaele SerraStefano de Franciscis
Aug 28, 2014·Journal of the American Heart Association·Bengt ZöllerKristina Sundquist
Jun 11, 2021·Circulation Research·Richard A BaylisEri Fukaya

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.