Family history of substance use disorders: Significance for mental health in young adults who gamble.

Journal of Behavioral Addictions
Jon E Grant, Samuel R Chamberlain

Abstract

Although family history of psychiatric disorders has often been considered potentially useful in understanding clinical presentations in patients, it is less clear what a positive family history means for people who gamble in the general community. We sought to understand the clinical and cognitive impact of having a first-degree relative with a substance use disorder (SUD) in a sample of non-treatment seeking young adults. 576 participants (aged 18-29 years) who gambled at least five times in the preceding year undertook clinical and neurocognitive evaluations. Those with a first-degree relative with a SUD were compared to those without on a number of demographic, clinical and cognitive measures. We used Partial Least Squares (PLS) regression to identify which variables (if any) were significantly associated with family history of SUDs, controlling for the influence of other variables on each other. 180 (31.3%) participants had a first-degree family member with a SUD. In terms of clinical variables, family history of SUD was significantly associated with higher rates of substance use (alcohol, nicotine), higher rates of problem gambling, and higher occurrence of mental health disorders. Family history of SUD was also associate...Continue Reading

References

Oct 1, 1977·Archives of General Psychiatry·N C AndreasenG Winokur
Jun 1, 1992·Alcoholism, Clinical and Experimental Research·D A DawsonB F Grant
Nov 1, 1991·The American Journal of Psychiatry·K S KendlerL J Eaves
Feb 1, 1990·Alcoholism, Clinical and Experimental Research·H de Wit, S G McCracken
Jan 1, 1990·Neuropsychologia·A M OwenT W Robbins
Jan 1, 1988·Addictive Behaviors·J E MitchellE Eckert
Jan 1, 1988·Behaviour Research and Therapy·E Sanavio
Jul 1, 1985·The British Journal of Psychiatry : the Journal of Mental Science·R W Latcham
Jul 1, 1984·Alcoholism, Clinical and Experimental Research·K W SchaefferJ R Yohman
Aug 1, 1981·Archives of General Psychiatry·C R CloningerS Sigvardsson
Jan 1, 1995·Journal of Studies on Alcohol·A I DrakeM A Schuckit
Nov 1, 1995·Journal of Clinical Psychology·J H PattonE S Barratt
Dec 20, 2003·Annals of the New York Academy of Sciences·John H KrystalD Cyril D'Souza
Sep 29, 2006·Neuropsychologia·Samuel R ChamberlainBarbara J Sahakian
Nov 6, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Adam R AronVeit Stuphorn
Mar 18, 2008·Alcoholism, Clinical and Experimental Research·Cheryl L BeselerDeborah S Hasin
May 24, 2011·Lancet·David C HodginsJon E Grant
Jul 1, 2011·Psychiatry Research·Jon Edgar GrantSuck Won Kim
Nov 26, 2011·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Michael HarringtonJames Bolton
Mar 27, 2013·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Wendy S SlutskeNicholas G Martin
Apr 20, 2014·Biological Psychiatry·Jillian E HardeeMary M Heitzeg
Oct 23, 2014·Annals of the New York Academy of Sciences·Luke Clark
May 7, 2015·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Kenneth S KendlerDanielle Dick
Nov 13, 2015·Drug and Alcohol Dependence·Anita Cservenka
Mar 21, 2016·Comprehensive Psychiatry·Sarah A ReddenJon E Grant
Jun 30, 2016·Journal of Psychiatric Research·Eric W LeppinkJon E Grant
Dec 6, 2017·Neuroscience and Biobehavioral Reviews·Tim van TimmerenAnna E Goudriaan
Dec 28, 2019·Progress in Neuro-psychopharmacology & Biological Psychiatry·Jon E Grant, Samuel R Chamberlain

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