Farming of Plant-Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals

Advances in Virology
Pit Sze Liew, Mohd Hair-Bejo

Abstract

Plants have been studied for the production of pharmaceutical compounds for more than two decades now. Ever since the plant-made poultry vaccine against Newcastle disease virus made a breakthrough and went all the way to obtain regulatory approval, research to use plants for expression and delivery of vaccine proteins for animals was intensified. Indeed, in view of the high production costs of veterinary vaccines, plants represent attractive biofactories and offer many promising advantages in the production of recombinant vaccine proteins. Furthermore, the possibility of conducting immunogenicity and challenge studies in target animals has greatly exaggerated the progress. Although there are no edible plant-produced animal vaccines in the market, plant-based vaccine technology has great potentials. In this review, development, uses, and advantages of plant-based recombinant protein production in various expression platforms are discussed. In addition, examples of plant-based veterinary vaccines showing strong indication in terms of efficacy in animal disease prevention are also described.

References

Dec 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·H S MasonC J Arntzen
Nov 2, 1989·Nature·A HiattK Bowdish
May 28, 1996·Proceedings of the National Academy of Sciences of the United States of America·H S MasonC J Arntzen
Mar 1, 1997·Nature Biotechnology·K DalsgaardP B Rodgers
Dec 1, 1995·Bio/technology·P B McGarveyF H Michaels
Oct 3, 1999·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·J KapustaA B Legocki
Feb 7, 2001·Current Opinion in Biotechnology·A M Walmsley, C J Arntzen
Apr 15, 2000·Dental Update·J K Ma
Oct 29, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·H BelangerV Yusibov
Dec 29, 2000·Nature·UNKNOWN Arabidopsis Genome Initiative
Mar 21, 2001·Vaccine·S J StreatfieldJ A Howard
Oct 18, 2001·Current Opinion in Biotechnology·G Giddings
Mar 6, 2002·Molecular Biotechnology·G Gary ZhangK Andrew White
Jul 5, 2002·Journal of Virology·Diane E WebsterSteve L Wesselingh
Jul 13, 2002·Trends in Molecular Medicine·Hugh S MasonCharles J Arntzen
Dec 5, 2002·Current Opinion in Structural Biology·Iain B H Wilson
Dec 14, 2002·Journal of Controlled Release : Official Journal of the Controlled Release Society·Barry J LamphearJohn A Howard
Jun 5, 2003·International Journal for Parasitology·Stephen J Streatfield, John A Howard
Nov 20, 2003·Trends in Biotechnology·Richard M TwymanRainer Fischer
Mar 9, 2004·Current Opinion in Plant Biology·Rainer FischerRichard M Twyman

❮ Previous
Next ❯

Citations

Mar 29, 2016·Developmental and Comparative Immunology·Carmen W E Embregts, Maria Forlenza
Jul 22, 2016·Plant Biotechnology Journal·Naila Shahid, Henry Daniell
May 31, 2017·Vaccines·Christopher ConchaCristian Ibáñez
Aug 5, 2017·Biology Letters·Chris Broeckhoven, Anton du Plessis
Aug 31, 2020·Clinical and Experimental Vaccine Research·Sayed Sartaj Sohrab
Jul 14, 2017·Scientific Reports·Takumi OgawaDaisaku Ohta
Feb 13, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Oksana SytarMarco Landi

❮ Previous
Next ❯

Methods Mentioned

BETA
transgenic

Software Mentioned

ProdiGene

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Biomedicine & Biotechnology
Marina Clemente, Mariana G Corigliano
Current Topics in Microbiology and Immunology
R W Hammond, L G Nemchinov
International Journal of Molecular Sciences
Agnieszka SirkoPatrycja Redkiewicz
© 2021 Meta ULC. All rights reserved