FASS is a better predictor of poor outcome in lower limb blast injury than AIS: implications for blast research

Journal of Orthopaedic Trauma
Maj Arul RamasamyJon C Clasper

Abstract

Due to the absence of clinical blast data, automotive injury data using the abbreviated injury score (AIS) has been extrapolated to define current North Atlantic Treaty Organisation (NATO) injury thresholds for anti-vehicle mine tests. We hypothesized that AIS, being a marker of fatality rather than disability, would be a worse predictor of poor clinical outcome compared with the lower limb-specific foot and ankle severity score (FASS). Using a prospectively collected trauma database, we identified UK Service Personnel sustaining lower leg injuries from under-vehicle explosions from January 2006 to December 2008. A full review of all medical documentation was performed to determine patient demographics and the severity of lower leg injury, as assessed by AIS and FASS. Clinical endpoints were defined as (1) need for amputation or (2) poor clinical outcome (defined as amputation or ongoing clinical problems). Statistical models were developed to explore the relationship between the scoring systems and clinical endpoints. Sixty-three UK casualties (89 limbs) were identified with a lower limb injury after under-vehicle explosion. The mean age of the casualty was 26.0 years. At 33.6 months follow-up, 29.1% (26 of 89) required an amp...Continue Reading

References

Mar 1, 1987·American Journal of Public Health·E J MacKenzieA Pitt
Oct 6, 1997·Foot & Ankle International·A ManoliR S Levine
Jan 19, 1999·Journal of Orthopaedic Trauma·D C TurchinJ P Waddell
Jan 12, 2000·The Orthopedic Clinics of North America·J M Wiater, E L Flatow
May 7, 2002·Foot & Ankle International·Trieu Tran, David Thordarson
Apr 7, 2007·Journal of Orthopaedic Trauma·Brett D OwensJoseph C Wenke
Jul 16, 2008·Journal of the Royal Army Medical Corps·Jason SmithJudith McLeod
Oct 14, 2008·The Journal of Trauma·Arul RamasamyMichael P M Stewart
May 12, 2009·The Journal of Trauma·Howard R ChampionLee Ann Young
Jul 3, 2009·Injury·Ayman M A TadrosFikri M Abu-Zidan
Oct 17, 2009·Annals of the Royal College of Surgeons of England·A RamasamyM Midwinter
Mar 2, 2010·Foot and Ankle Clinics·Eric M Bluman, James R Ficke
Mar 2, 2010·Foot and Ankle Clinics·Eric M BlumanDana C Covey
May 22, 2010·The Journal of Trauma·Hans-Christoph PapeNicola-Alexander Sittaro
Jan 15, 2011·Injury·Patricia FarrugiaBrad A Petrisor

❮ Previous
Next ❯

Citations

Sep 26, 2013·The Journal of Trauma and Acute Care Surgery·Mary M LawnickStephen Flaherty
Oct 30, 2018·Military Medicine·Susan L EskridgeMichael R Galarneau
Oct 3, 2018·Annals of Biomedical Engineering·Grigoris GrigoriadisSpyros D Masouros

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Wilderness & Environmental Medicine
George W Rodway, Stephen R Muza
Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association
David M LamGary R Gilbert
Environmental Science and Pollution Research International
Dragana PopovicSlavica Rajsic
© 2021 Meta ULC. All rights reserved