Fast (13)C-glucose metabolite mapping in rat brain using (1)H echo planar spectroscopic imaging technique at 2T

Journal of Magnetic Resonance Imaging : JMRI
S Morikawa, T Inubushi

Abstract

For fast (13)C metabolite mapping in rat brains, (1)H-detected (13)C NMR spectroscopy using gradient-enhanced heteronuclear multiple-quantum coherence and (1)H echo planar spectroscopic imaging were combined. (13)C glucose and 3-/4-(13)C-Glu/Gln images of rat brain were successfully constructed with 35-minute temporal resolution under a 2T magnetic field. In the ischemic region of the suture middle cerebral artery occlusion model, glucose and Glu/Gln signals decreased and lactate signals appeared. J. Magn. Reson. Imaging 2001;13:787-791.

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Citations

Apr 23, 2002·NMR in Biomedicine
May 28, 2005·Magnetic Resonance Imaging·Francesco de PasqualeFrancesco De Luca
Jul 14, 2006·Proceedings of the National Academy of Sciences of the United States of America·Klaes GolmanMikkel Thaning
Apr 12, 2002·Journal of Magnetic Resonance·Alex M J HudsonRichard Bowtell
Jun 9, 2016·Oxidative Medicine and Cellular Longevity·Mengting LiuHongjun Yang

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