Fast and accurate long-read alignment with Burrows-Wheeler transform

Bioinformatics
Heng Li, Richard Durbin

Abstract

Many programs for aligning short sequencing reads to a reference genome have been developed in the last 2 years. Most of them are very efficient for short reads but inefficient or not applicable for reads >200 bp because the algorithms are heavily and specifically tuned for short queries with low sequencing error rate. However, some sequencing platforms already produce longer reads and others are expected to become available soon. For longer reads, hashing-based software such as BLAT and SSAHA2 remain the only choices. Nonetheless, these methods are substantially slower than short-read aligners in terms of aligned bases per unit time. We designed and implemented a new algorithm, Burrows-Wheeler Aligner's Smith-Waterman Alignment (BWA-SW), to align long sequences up to 1 Mb against a large sequence database (e.g. the human genome) with a few gigabytes of memory. The algorithm is as accurate as SSAHA2, more accurate than BLAT, and is several to tens of times faster than both. http://bio-bwa.sourceforge.net

References

Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·W R Pearson, D J Lipman
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Jul 13, 2000·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Z ZhangW Miller
Oct 10, 2001·Genome Research·Zemin NingJames C Mullikin
Apr 5, 2002·Genome Research·W J Kent
Apr 6, 2002·Bioinformatics·Bin MaMing Li
Jan 30, 2008·Bioinformatics·Ruiqiang LiJun Wang
Jan 30, 2008·Bioinformatics·T W LamS M Yiu
Mar 1, 2008·BMC Bioinformatics·Andrew D SmithMichael Q Zhang
Jun 24, 2008·Bioinformatics·Aleksandr MorgulisAlejandro A Schäffer
Aug 8, 2008·Bioinformatics·Hao LinMing Li
Aug 14, 2008·Bioinformatics·Hui Jiang, Wing Hung Wong
Nov 22, 2008·Science·John EidStephen Turner
Mar 6, 2009·Genome Biology·Ben LangmeadSteven L Salzberg
May 20, 2009·Bioinformatics·Heng Li, Richard Durbin
May 23, 2009·PLoS Computational Biology·Stephen M RumbleMichael Brudno
Jun 10, 2009·Bioinformatics·Heng Li1000 Genome Project Data Processing Subgroup
Jul 14, 2009·Genome Research·David WeeseKnut Reinert

Citations

Aug 7, 2013·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Jennifer SpindelSusan McCouch
Jul 20, 2012·Journal of Molecular Evolution·Cynthia M McDonnellBarry R Pittendrigh
Dec 17, 2010·Mammalian Genome : Official Journal of the International Mammalian Genome Society·John P FlahertyDavid E Bergstrom
Sep 20, 2012·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Michelle M SimonLaura G Reinholdt
May 9, 2013·World Journal of Microbiology & Biotechnology·Asifullah KhanM Kamran Azim
Sep 8, 2012·Journal of Cardiovascular Translational Research·James S WareStuart A Cook
Jun 10, 2011·European Journal of Human Genetics : EJHG·Sara J BownePeter Humphries
Mar 2, 2012·European Journal of Human Genetics : EJHG·Andreas LeidenrothJane E Hewitt
Mar 15, 2013·European Journal of Human Genetics : EJHG·Michael A GonzalezRebecca Schule
Aug 11, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Mark D AdamsJoseph Willis
Jun 23, 2012·Nature·Philip J StephensMichael R Stratton
Jun 16, 2012·Nature·Human Microbiome Project Consortium
Dec 20, 2011·Nature Biotechnology·Joke ReumersJurgen Del-Favero
Apr 24, 2012·Nature Biotechnology·Nicholas J LomanMark J Pallen
Nov 10, 2012·Nature Biotechnology·Jay Shendure, Erez Lieberman Aiden
Nov 5, 2013·Nature Biotechnology·Joshua N BurtonJay Shendure
Dec 10, 2013·Nature Biotechnology·Osmat A JeffersonRichard A Jefferson
Mar 20, 2012·Nature Cell Biology·Marzia FumagalliFabrizio d'Adda di Fagagna
May 16, 2013·Nature Communications·Guo-Dong WangYa-Ping Zhang
Jan 11, 2012·Nature Genetics·Zamin IqbalGil McVean
Nov 13, 2012·Nature Genetics·Cassandra LoveSandeep S Dave
Nov 28, 2012·Nature Genetics·Qiang XuYijun Ruan
Dec 12, 2012·Nature Genetics·Tania FuchsLaurie J Ozelius
Feb 26, 2013·Nature Genetics·Giulio GenoveseSteven A McCarroll
Jul 31, 2013·Nature Genetics·Christie M BuchoveckyMonica J Justice
Sep 17, 2013·Nature Genetics·Dong hyun KimAlexander van Oudenaarden
Sep 17, 2013·Nature Genetics·Enrico LeipoldIngo Kurth
Nov 5, 2013·Nature Genetics·Joshua M FrancisMatthew Meyerson
Nov 12, 2013·Nature Genetics·Huayang TangXuejun Zhang
Feb 15, 2011·Nature Genetics·Robert E HandsakerSteven A McCarroll
Jan 13, 2012·Nature Medicine·Panagiotis NtziachristosIannis Aifantis
Mar 6, 2012·Nature Methods·Ben Langmead, Steven L Salzberg
Oct 30, 2012·Nature Methods·Santiago Marco-SolaPaolo Ribeca
Dec 12, 2012·Nature Methods·Gregory G Faust, Ira M Hall
Jan 8, 2013·Nature Methods·Gokul RamaswamiJin Billy Li
Nov 30, 2011·Nature Reviews. Genetics·Todd J Treangen, Steven L Salzberg
Apr 19, 2013·Nature Reviews. Genetics·Bonnie BergerMona Singh
Dec 11, 2013·Nature Reviews. Genetics·Kimberly RobaskyGeorge M Church
Nov 12, 2013·Nature Structural & Molecular Biology·Young-Kook KimV Narry Kim
Dec 12, 2012·The New England Journal of Medicine·Michael E TalkowskiCynthia C Morton
Nov 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Ruibin XiPeter J Park
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Shu-Dan YehJosé M Ranz
Sep 6, 2012·Proceedings of the National Academy of Sciences of the United States of America·Wen HuangTrudy F C Mackay
Oct 19, 2012·Proceedings of the National Academy of Sciences of the United States of America·Way SungMichael Lynch
Jun 19, 2013·Proceedings of the National Academy of Sciences of the United States of America·Ana R BezerraManuel A S Santos
Oct 2, 2013·Proceedings of the National Academy of Sciences of the United States of America·Kathryn E HoltStephen Baker
Jun 15, 2011·The Journal of Experimental Medicine·Giulia FabbriGianluca Gaidano
Oct 16, 2013·The Journal of Experimental Medicine·Giulia FabbriRiccardo Dalla-Favera
Jun 6, 2013·Astrobiology·Christopher E CarrGary Ruvkun
Nov 6, 2013·Biosecurity and Bioterrorism : Biodefense Strategy, Practice, and Science·Oskar Erik KarlssonFredrik Granberg
Oct 23, 2013·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Itamar EskinEran Halperin
Sep 17, 2011·Omics : a Journal of Integrative Biology·Joaquín AriñoJoaquin Dopazo
Jan 27, 2011·Briefings in Functional Genomics·Martin Hirst, Marco A Marra
May 13, 2010·Briefings in Bioinformatics·Heng Li, Nils Homer
Apr 21, 2011·Briefings in Bioinformatics·Paolo Ribeca, Gabriel Valiente
Sep 11, 2012·Briefings in Bioinformatics·Sharmila S MandeTarini Shankar Ghosh
Apr 10, 2010·Bioinformatics·Anna RitzBenjamin J Raphael
Jun 10, 2010·Bioinformatics·Jared T Simpson, Richard Durbin
Sep 9, 2010·Bioinformatics·Abhilash SrikanthaRangavittal Narayanan
Aug 27, 2010·Bioinformatics·Guillaume Rizk, Dominique Lavenier
Feb 26, 2011·Bioinformatics·Hans-Ulrich KleinMartin Dugas
Jun 15, 2011·Bioinformatics·Ofer IsakovNoam Shomron
Aug 23, 2011·Bioinformatics·Matthew RuffaloMehmet Koyutürk
Dec 14, 2011·Bioinformatics·Robert SchmiederRobert Edwards
Apr 18, 2012·Bioinformatics·Xuesong HuWei Fan
Jun 13, 2012·Bioinformatics·Chandana TennakoonWing-Kin Sung
Sep 11, 2012·Bioinformatics·Yongchao Liu, Bertil Schmidt
Jul 20, 2012·Bioinformatics·John C MuWing H Wong
Jul 26, 2012·Bioinformatics·Gregory G Faust, Ira M Hall
Oct 13, 2012·Bioinformatics·Nuno A FonsecaJohn C Marioni
Dec 26, 2012·Bioinformatics·Paul M GontarzChung F Wong
Jun 12, 2013·Bioinformatics·Christos KozanitisVineet Bafna
Jul 19, 2013·Bioinformatics·Manuel A RivasPeter Donnelly
Aug 27, 2013·Bioinformatics·Fritz J SedlazeckArndt von Haeseler
Nov 29, 2011·Brain : a Journal of Neurology·Junling WangBeisha Tang
May 12, 2012·Brain : a Journal of Neurology·Gerald PfefferPatrick F Chinnery
May 28, 2013·Database : the Journal of Biological Databases and Curation·Gaëtan DrocStéphanie Bocs
Dec 24, 2011·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Yu KanesakiHirofumi Yoshikawa
May 10, 2013·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Hideki NagasakiYasukazu Nakamura
Jul 3, 2013·Genome Biology and Evolution·Wen-Lang FanWen-Hsiung Li
Feb 1, 2013·Molecular Biology and Evolution·Darren KessnerJohn Novembre
Oct 1, 2013·Molecular Biology and Evolution·Zechen ChongChung-I Wu
May 18, 2011·Nucleic Acids Research·Kensuke NakamuraShigehiko Kanaya
Mar 2, 2012·Nucleic Acids Research·Gong ZhangZoya Ignatova
Oct 16, 2012·Nucleic Acids Research·Niko Popitsch, Arndt von Haeseler
Apr 6, 2013·Nucleic Acids Research·Yang LiaoWei Shi
May 24, 2013·Nucleic Acids Research·Feng ZengTing Chen
Aug 11, 2012·Molecular Plant-microbe Interactions : MPMI·Aureliano BombarelyGregory B Martin
Jan 5, 2012·Journal of Pediatric Hematology/oncology·Louise BorstKjeld Schmiegelow
Apr 13, 2011·Genome Research·Wei-Chun KaoYun S Song
Dec 3, 2011·Genome Research·Daniel R SchriderMatthew W Hahn
Oct 20, 2011·Genome Research·Mauro CastellarinRobert A Holt
Dec 14, 2011·Genome Research·Jared T Simpson, Richard Durbin
Nov 17, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Rebecca CullumPamela A Hoodless
Jul 30, 2011·Science·Nicolas StranskyJennifer R Grandis
Apr 28, 2012·Science·Pontus SkoglundMattias Jakobsson
Mar 17, 2012·Science·Adam AutonGil McVean
Sep 1, 2012·Science·Kasavajhala V S K PrasadThomas Mitchell-Olds
Mar 16, 2013·Science·Catherine R LinnenHopi E Hoekstra
Oct 19, 2013·Science·Maya KasowskiMichael Snyder
Jun 19, 2013·Applied and Environmental Microbiology·Karl-Magnus AnderssonAnders Tunlid
Mar 31, 2012·Journal of Bacteriology·Su Yean OngMaqsudul Alam
May 10, 2011·Journal of Bacteriology·Yanxia LiLei Wang
Oct 30, 2012·Journal of Bacteriology·Joana RevezMarja-Liisa Hänninen
Nov 13, 2012·Journal of Bacteriology·Qiliang LaiZongze Shao
Nov 13, 2012·Journal of Bacteriology·Qiliang LaiZongze Shao
May 24, 2011·Journal of Bacteriology·Jiabo DingBaoli Zhu
Nov 1, 2011·Journal of Bacteriology·Hongseok TaeHarold R Garner
Sep 21, 2012·Journal of Clinical Microbiology·Astrid GallPaul Kellam
Dec 12, 2012·Molecular and Cellular Biology·Karen E HaydenHuntington F Willard
Jul 25, 2013·Journal of Medical Genetics·Kevin P KennaOrla Hardiman
Jul 20, 2012·Journal of Bioinformatics and Computational Biology·Kouichi KimuraKenta Nakai
May 16, 2013·American Journal of Respiratory Cell and Molecular Biology·Philip ThaiReen Wu
Apr 2, 2013·The Journal of Clinical Investigation·Mustafa TekinAndrew H Crosby
Jun 16, 2011·BMC Bioinformatics·Francisco FernandesAna T Freitas
Sep 21, 2012·BMC Bioinformatics·Emanuele RaineriMiguel Pérez-Enciso
Jun 14, 2013·BMC Bioinformatics·Manuel AllhoffTobias Marschall
Jun 14, 2013·BMC Bioinformatics·Christine LoVineet Bafna
Feb 22, 2011·BMC Genomics·Nicholas J CroucherStephen D Bentley
Jul 27, 2011·BMC Genomics·Zhengdong D ZhangMark B Gerstein
Mar 6, 2012·BMC Genomics·Danny C C PooJames T L Mah
Jun 26, 2012·BMC Genomics·Jose M BlancaBelén Picó
Jul 24, 2012·BMC Genomics·Karen E Hayden, Huntington F Willard
Jul 26, 2012·BMC Genomics·Michael InouyeKathryn E Holt
Sep 11, 2012·BMC Genomics·Jérôme MarietteChristophe Klopp
Oct 2, 2013·BMC Genomics·Pablo CingolaniDouglas Ruden
Dec 18, 2013·BMC Genomics·Andrezza C ChagasJosé M C Ribeiro
Oct 11, 2012·BMC Medical Genetics·Andrew T DeWanMichael B Bracken
Feb 15, 2013·Biological Procedures Online·Derek Shyr, Qi Liu
Nov 21, 2013·Algorithms for Molecular Biology : AMB·Sebastian Deorowicz, Szymon Grabowski
Apr 5, 2013·Biotechnology for Biofuels·Daniel González-RamosJean-Marc G Daran
Jun 8, 2011·BMC Research Notes·Tung NguyenDouglas Ruden
Jan 24, 2013·BMC Research Notes·Paulo G S da FonsecaAna T Freitas
Sep 6, 2013·Epigenetics & Chromatin·Marcin CieślikStefan Bekiranov
Jan 2, 2013·Mobile DNA·Jeremy DufourtChantal Vaury
Jan 24, 2014·Microbiome·René L WarrenRobert A Holt
Sep 17, 2011·Genome Biology·Nathan O StitzielShamil R Sunyaev
Oct 1, 2011·Genome Biology·Anna-Maija SulonenJanna Saarela
Nov 2, 2012·Genome Biology·Yogesh SaletoreChristopher E Mason
Dec 15, 2012·Genome Biology·Niranjan NagarajanYijun Ruan
Aug 25, 2012·Genome Biology·Kim WongThomas M Keane
Mar 30, 2013·Genome Biology·Nicolas PhilippeEric Rivals
May 31, 2013·Genome Biology·Michael G RossDavid B Jaffe
Aug 31, 2013·Genome Biology·Sangwoo KimVineet Bafna
Jul 27, 2012·RNA·Claudia L KleinmanJacek Majewski
Jan 10, 2013·PLoS Computational Biology·Xochitl C Morgan, Curtis Huttenhower
May 17, 2014·PLoS Computational Biology·Nicolas AltemoseHuntington F Willard
Oct 17, 2012·PLoS Genetics·Josep M ComeronSamuel Bailin
Jan 30, 2013·PLoS Genetics·Yun-Ching ChenRachel Karchin
Nov 28, 2013·PLoS Neglected Tropical Diseases·Jean-François RittMarc Ouellette
May 17, 2011·PloS One·Silvia QueringsRoman K Thomas
Oct 15, 2011·PloS One·Matthias Zytnicki, Hadi Quesneville
Apr 25, 2012·PloS One·Brandon R MenziesAndrew J Pask
Apr 27, 2012·PloS One·John W ColeJeffrey R O'Connell
May 11, 2012·PloS One·Shuji SuzukiYutaka Akiyama
Jun 8, 2012·PloS One·Zeynep Kalender AtakStein Aerts
Jan 4, 2013·PloS One·Rafael Valdés-MasXose S Puente
Jan 10, 2013·PloS One·Robert Lindner, Caroline C Friedel
Jun 7, 2013·PloS One·Ruibang LuoTak-Wah Lam
Jul 11, 2013·PloS One·Timothy T PerkinsBarry Marshall
Jul 12, 2013·PloS One·Felix E Enciso-RodríguezLeonardo Mariño-Ramírez
Sep 12, 2013·PloS One·Jill L WegrzynKristian A Stevens
Sep 11, 2013·PloS One·Thomas BonfertCaroline C Friedel
Aug 11, 2011·PLoS Pathogens·Joshua Chang MellRosemary J Redfield
May 17, 2014·PLoS Pathogens·Dina AlzhanovaKlaus Früh
Oct 12, 2012·Genetics·Gregory MinevichOliver Hobert
Jul 31, 2012·Emerging Infectious Diseases·Erin P PricePaul Keim
Jan 17, 2014·Nature·Aruna KodeStavroula Kousteni
Mar 19, 2014·Nature Methods·Andrew RothSohrab P Shah
Jan 25, 2014·Molecular Biology and Evolution·Jeanmaire MolinaMichael D Purugganan
Dec 7, 2013·Molecular Biology and Evolution·Masafumi NozawaTakashi Gojobori
Jan 3, 2014·The Journal of Clinical Investigation·Jerome E RogerAnand Swaroop
Feb 4, 2014·Diagnostic Pathology·Guangxin LiZhenhai Yu
Mar 7, 2014·Nature Communications·Lincoln T ShenjeDaniel P Judge
Feb 12, 2013·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Marie PegelowM Peyrard-Janvid
Mar 19, 2014·Nature Genetics·Sam BehjatiPeter J Campbell
Nov 1, 2013·Proceedings of the National Academy of Sciences of the United States of America·Leonid TeytelmanAlexander van Oudenaarden
Jun 15, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Mark A UmbargerGregory J Porreca
Nov 6, 2013·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Wei ChenHang He
Jan 24, 2013·Briefings in Bioinformatics·Stephan PabingerZlatko Trajanoski
Dec 18, 2013·Genome Biology and Evolution·Lex E FlagelTodd J Vision
Nov 22, 2013·Genome Biology and Evolution·Molly K BurkeAnthony D Long
Oct 23, 2013·Proceedings of the National Academy of Sciences of the United States of America·Amy Cunningham-BusselCarl F Nathan
Dec 18, 2013·AIDS·Guoqin YuJames J Goedert
Jan 31, 2014·BMC Genomics·Sean R LandmanVipin Kumar
Mar 19, 2013·Annals of the Rheumatic Diseases·Monique StoffelsJos W M van der Meer
Nov 20, 2013·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Samantha BaldwinJohn McCallum
Apr 30, 2014·BioMed Research International·Jing ShangBairong Shen
Jan 17, 2014·Nature Communications·Niccolo BolliNikhil Munshi
Feb 1, 2013·TheScientificWorldJournal·Marisa P Dolled-FilhartJimmy Cheng-Ho Lin
Dec 10, 2013·Journal of Medical Genetics·Talya DorSimon Edvardson
Apr 9, 2013·Annual Review of Analytical Chemistry·Elaine R Mardis
Apr 22, 2014·Nature Genetics·Caroline NavaChristel Depienne
Jul 4, 2013·Nucleic Acids Research·Jose P Lopez-AtalayaAngel Barco
Mar 15, 2014·Bioinformatics·Christian OttoSteve Hoffmann
Jan 28, 2014·Proceedings of the National Academy of Sciences of the United States of America·Catarina CardosoCarolien Ruyter-Spira
Mar 13, 2014·Molecular Biology and Evolution·Homa Papoli Yazdi, Hans Ellegren
Jan 25, 2014·Genome Announcements·Vítor BorgesJoão P Gomes
Oct 10, 2013·European Journal of Human Genetics : EJHG·Zippora BrownsteinKaren B Avraham
Oct 10, 2013·European Journal of Human Genetics : EJHG·Hui ZhaoPhilip Van Damme
Jan 21, 2014·Bioinformatics·Moritz GerstungPeter J Campbell
Jan 2, 2014·Omics : a Journal of Integrative Biology·Xi QianGuofang Zhong
Jun 5, 2014·BMC Bioinformatics·Ranjan Kumar MajiZhumur Ghosh
May 3, 2014·Genome Biology and Evolution·Md Tauqeer AlamTimothy D Read
Apr 22, 2014·Nature Methods·Dominic GrünAlexander van Oudenaarden
Jun 13, 2014·Proceedings. Biological Sciences·Martijn J T N TimmermansAlfried P Vogler
Apr 10, 2014·Nature Communications·Susanna L CookeICGC Breast Cancer Group
Apr 9, 2014·Genome Biology and Evolution·Rochelle M SooPhilip Hugenholtz
Apr 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·Kerensa E McElroyTorsten Thomas
Jun 3, 2014·Nature Communications·Michael R GreenIsidro Sánchez-García
Jun 2, 2014·Genome Biology and Evolution·Sutada MungpakdeeEiichi Shoguchi
Dec 18, 2013·Proceedings of the National Academy of Sciences of the United States of America·Iuliana Ionita-LazaMaria Karayiorgou
Jun 16, 2014·Nature Genetics·Aaron R JexRobin B Gasser
Aug 27, 2013·Brain Imaging and Behavior·Ivo D DinovAlzheimer’s Disease Neuroimaging Initiative
Sep 7, 2014·BMC Genomics·János MolnárEndre Barta
Jul 30, 2014·Proceedings of the National Academy of Sciences of the United States of America·Antonio L AmelioMichael D Conkright
Jan 23, 2014·European Journal of Human Genetics : EJHG·Shengting LiMikkel H Schierup
Jun 12, 2014·Molecular Biology and Evolution·Qu Zhang, Bing Su
Jun 14, 2014·Genome Biology and Evolution·Katrin RademacherBernhard Horsthemke
Jun 28, 2014·Genome Announcements·Kent D KawashimaFilipinas F Natividad
Jul 26, 2014·Genetic Testing and Molecular Biomarkers·Guney BademciMustafa Tekin
Feb 8, 2014·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Trevor J PughBirgit H Funke
Nov 26, 2013·Human Molecular Genetics·Magdalena E TyburczyThomas N Darling
Aug 5, 2014·Nature Genetics·Kaitlin E SamochaMark J Daly
Jul 10, 2014·Nature Communications·Yujun ShengXuejun Zhang
Sep 28, 2014·BMC Genomics·Anselmo Azevedo SantosMaria Lucia Carneiro Vieira
Sep 17, 2014·Nature Communications·Nicholas J TimpsonUK1OK Consortium Members
Oct 8, 2014·PeerJ·Johannes Köster, Sven Rahmann
Aug 19, 2014·Nature Methods·Giuseppe NarzisiMichael C Schatz
Aug 19, 2014·Nature Genetics·Kaan BoztugChristoph Klein
Jul 17, 2014·Bioinformatics·Kathrin TrappeKnut Reinert
Oct 1, 2014·Nature Reviews. Genetics·David S GuttmanPaul Schulze-Lefert
Jul 20, 2014·Briefings in Functional Genomics·María Victoria Aguilar-PontesMiaomiao Zhou
Nov 6, 2014·Bioinformatics·Manuel AllhoffIvan G Costa
Dec 7, 2014·BMC Genomics·Ravi Vijaya Satya, John DiCarlo
Oct 11, 2014·Genome Announcements·Jan-Hendrik TrösemeierSally A Baylis
Oct 14, 2014·Nature Communications·Eduard SchulzHeinz Sill
Apr 20, 2014·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Stephen J SalipanteDavid Wu
Apr 1, 2014·Nucleic Acids Research·Jorge DuitamaGuy Froyen
Jun 6, 2014·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Helen R GriffinPatrick F Chinnery
Oct 1, 2014·BMC Genomics·Waibhav D TembeJohn D Carpten
Aug 3, 2013·Briefings in Bioinformatics·Irene KouskoumvekakiSøren Brunak
Dec 18, 2014·International Journal for Parasitology. Drugs and Drug Resistance·Andrew C KotzeRoger K Prichard
Jun 21, 2014·Bioinformatics·Bahlul HaiderChongle Pan
Dec 17, 2014·Nature Communications·Salvatore SimminiJacqueline Deschamps
Oct 30, 2014·Nature Communications·Ghislaine SceloG Mark Lathrop
Oct 18, 2014·Genome Announcements·Micheál Mac AogáinRonan F O'Toole
Jun 13, 2014·Bioinformatics·Paul GreenfieldDenis C Bauer
Nov 27, 2014·Nature Communications·Emilie E L MullerPaul Wilmes
Oct 23, 2013·Methods : a Companion to Methods in Enzymology·Paul RyvkinLi-San Wang
Sep 24, 2013·Genome Research·Nicola E PotterMel Greaves
Jun 19, 2013·Nature Genetics·Patrick S TarpeyP Andrew Futreal
Jun 19, 2013·Nature Genetics·Alanna C MorrisonCohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Consortium
Apr 12, 2012·Briefings in Bioinformatics·Xiao YangSrinivas Aluru
Sep 18, 2010·Nature Reviews. Genetics·Matthew MeyersonGad Getz
Aug 19, 2011·Human Heredity·Tommaso PippucciGiovanni Romeo
Nov 25, 2015·Cell Systems·Ebrahim AfshinnekooChristopher E Mason
Nov 25, 2015·Biotechnology Advances·Namitha MohandasRobin B Gasser
Dec 22, 2015·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Badar Abdul RazzaqA A Toor
Feb 18, 2016·Haemophilia : the Official Journal of the World Federation of Hemophilia·J M BastidaJ R González-Porras
Feb 19, 2016·Genome Biology·Tomislav IlicicSarah A Teichmann
Feb 2, 2016·Nature Biotechnology·Grace X Y ZhengHanlee P Ji
Jun 23, 2015·Nature Medicine·Lucy R YatesPeter J Campbell
Feb 18, 2016·BMC Musculoskeletal Disorders·Akshatha DesaiHakon Hakonarson
Nov 17, 2015·Bioinformatics·Bo LiuYadong Wang
Jan 23, 2016·Forensic Science International. Genetics·Eun Hye KimKyoung-Jin Shin
Mar 5, 2016·Veterinary Microbiology·Pimlapas LeekitcharoenphonFrank M Aarestrup
Jul 31, 2013·Expert Review of Molecular Diagnostics·Emily M CoonrodMartin G Reese
Feb 19, 2016·Scientific Reports·Wei QuShinichi Morishita
Feb 13, 2016·American Journal of Medical Genetics. Part a·Alexandra TopaCarola Hedberg-Oldfors
Feb 14, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Carla CossuMaria Cristina Rosatelli
Jan 9, 2016·Science·Frank MaixnerAlbert Zink
Feb 24, 2016·Frontiers in Genetics·Daniel LangenkämperTim W Nattkemper
Dec 25, 2015·Proceedings of the National Academy of Sciences of the United States of America·Clare D MarsdenKirk E Lohmueller
Feb 2, 2016·Mutation Research·Matthew S HestandJoris R Vermeesch
Feb 10, 2016·Scientific Reports·Lei ZhuZbynek Bozdech
Jan 29, 2016·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Martin SokolFinn Skou Pedersen
Feb 20, 2016·Nature Communications·Michael RamirezSteven J Altschuler
Oct 16, 2015·International Journal of Molecular Medicine·Yue ZhaoXue-Shan Xia
Dec 2, 2015·Oncology Letters·Shaomin LiZhe Qiao
Oct 16, 2015·Proceedings of the National Academy of Sciences of the United States of America·Harriet AlexanderSonya T Dyhrman
Apr 12, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Tatsuji MizukamiTakashi Kohno
Feb 5, 2016·Parasites & Vectors·Namitha MohandasRobin B Gasser
Jan 13, 2016·Proceedings of the National Academy of Sciences of the United States of America·David A GalbraithChristina M Grozinger
Jan 9, 2016·Biotechnology for Biofuels·Hong LuoJingchu Luo
Nov 10, 2013·Nucleic Acids Research·Katherine HuangNicola Segata
Dec 30, 2015·Journal of Molecular Biology·David SeifertKarin J Metzner
Feb 26, 2015·BMC Medical Genetics·Heather M McLaughlinMedSeq Project
Jun 10, 2015·Journal of Applied Genetics·M Mielczarek, J Szyda
Jan 30, 2016·Journal of the National Cancer Institute·Paul D P PharoahSusan J Ramus
Dec 26, 2015·Neurobiology of Aging·Changhe ShiYu-Ming Xu
Jul 24, 2015·ELife·Zhenghua ZhangZhengwen Jiang
Jan 31, 2016·The Journal of Pediatrics·Grace YoonFinding of Rare Disease Genes (FORGE) in Canada Consortium Steering Committee
Dec 18, 2013·Cancer Genetics·Fengqi Chang, Marilyn M Li
Mar 16, 2016·Molecular Metabolism·Amanda M AckermannKlaus H Kaestner
Dec 3, 2015·Proceedings of the National Academy of Sciences of the United States of America·E Sally ChangPaulyn Cartwright
Jan 23, 2016·Genome Announcements·Konstantinos V PapageorgiouSpyridon K Kritas
Apr 15, 2015·Proceedings of the National Academy of Sciences of the United States of America·Harriet AlexanderSonya T Dyhrman