Abstract
In this study, an efficient, fast and sensitive method for the simultaneous determination of eleven synthetic color additives (Allura red, Amaranth, Azo rubine, Brilliant blue, Erythrosine, Indigotine, Ponceau 4R, New red, Sunset yellow, Quinoline yellow and Tartrazine) in flour and meat foodstuffs is developed and validated using HPLC coupled with DAD and MS/MS. The color additives were extracted with ammonia-methanol and was further purified with SPE procedure using Strata-AW column in order to reduce matrix interference. This HPLC-DAD method is intended for a comprehensive survey of color additives in foods. HPLC-MS/MS method was used as the further confirmation and identification. Validation data showed the good recoveries in the range of 75.2-113.8%, with relative standard deviations less than 15%. These methods are suitable for the routine monitoring analysis of eleven synthetic color additives due to its sensitivity, reasonable time and cost.
References
Mar 15, 1978·International Journal of Cancer. Journal International Du Cancer·P J PriceR J Huebner
Jul 1, 1980·Toxicology and Applied Pharmacology·J F RobensJ F Douglas
Apr 3, 2003·Journal of Agricultural and Food Chemistry·Mónica GonzálezMiguel Valcárcel
Dec 13, 2005·Journal of Chromatography. a·Ming MaShouzhuo Yao
Mar 28, 2007·Analytica Chimica Acta·Katerina S MiniotiNikolaos S Thomaidis
Mar 29, 2008·Talanta·N Yoshioka, K Ichihashi
Mar 13, 2010·Analytical and Bioanalytical Chemistry·C Ferrer AmateS Masselter
Feb 16, 2013·Food Chemistry·Tingting ZouZhen Li
Mar 27, 2013·Journal of Agricultural and Food Chemistry·Bhakti Petigara HarpJulie N Barrows
Oct 17, 2013·Food Chemistry·Yonghong ZhuShiqi Chen
Sep 1, 2010·Food Additives & Contaminants. Part B, Surveillance·Kris Yuet-Wan LokJean Woo
Citations
Jun 24, 2015·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Rouhollah HeydariSanaz Zarabi
Jun 16, 2016·Frontiers in Microbiology·Kobun RovinaSharifudin M Shaarani
Jan 28, 2017·Critical Reviews in Analytical Chemistry·Kobun RovinaSharifudin Md Shaarani
Feb 15, 2017·Applied Spectroscopy·Erin ArrozGerard G Dumancas
Jul 6, 2018·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Xue WangZhi-Qi Zhang
Mar 31, 2019·Journal of Chromatographic Science·Dongmei ChenZonghui Yuan
Oct 24, 2018·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Xiaoting ZhangMinghua Lu
Nov 5, 2019·Food Chemistry·Zhibo HuChunyuan Li
Feb 8, 2021·Food Chemistry·Hassan Refat H AliMohamed M El-Wekil
May 12, 2021·Food Chemistry·Ping QiJi-Jun Jiang
Jul 10, 2021·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Stephen W C Chung