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Fast Green FCF Attenuates Lipopolysaccharide-Induced Depressive-Like Behavior and Downregulates TLR4/Myd88/NF-κB Signal Pathway in the Mouse Hippocampus

Frontiers in Pharmacology

May 8, 2019

Jing YangXiaowei Chen

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Abstract

Depression is a common neuropsychiatric disorder and new anti-depressive treatments are still in urgent demand. Fast Green FCF, a safe biocompatible color additive, has been suggested to mitigate chronic pain. However, Fast green FCF's effect on depression is unknown. We aimed to invest...read more

Mentioned in this Paper

Biomaterials
Brain
Mental Depression
Depressive Disorder
Down-Regulation
Hippocampus (Brain)
Inflammation
Interleukin-1
Interleukin-6
Lipopolysaccharides
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1
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Fast Green FCF Attenuates Lipopolysaccharide-Induced Depressive-Like Behavior and Downregulates TLR4/Myd88/NF-κB Signal Pathway in the Mouse Hippocampus

Frontiers in Pharmacology

May 8, 2019

Jing YangXiaowei Chen

PMID: 31139084

DOI: 10.3389/fphar.2019.00501

Abstract

Depression is a common neuropsychiatric disorder and new anti-depressive treatments are still in urgent demand. Fast Green FCF, a safe biocompatible color additive, has been suggested to mitigate chronic pain. However, Fast green FCF's effect on depression is unknown. We aimed to invest...read more

Mentioned in this Paper

Biomaterials
Brain
Mental Depression
Depressive Disorder
Down-Regulation
1
1

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