Mar 12, 2004

Fast pathway-His bundle connections in the rabbit heart

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing
Eugene Patterson, Benjamin J Scherlag

Abstract

The incidence and the physiologic roles for direct fast pathway-His bundle connections were examined in 102 rabbit hearts. Extracellular bipolar and intracellular microelectrode recordings were made from the superfused rabbit AV junction. In 13 of 27 preparations demonstrating anterior extensions of the fast pathway, the retrograde HA ERP and 2:1 block cycle length were shortened (128 +/- 12 and 145 +/- 5 msec, respectively) versus the remaining 89 preparations (178 +/- 15 and 185 +/- 10 msec, respectively, p < 0.01). The former values were similar to the ERP and 2:1 block cycle length of fast pathway transitional cells (128 +/- 23 and 141 +/- 4 msec, respectively), suggestive of a direct fast pathway-His bundle connection. A deflection recorded between the A and H potentials of the His bundle electrogram could be dissociated from both atrial and His bundle activation. Intracellular microelectrode recordings and light microscopy confirmed the deflection to be an accessory pathway consisting of an anterior extension of fast pathway transitional cells connecting the atrium and His bundle. Transection along the AV groove anterior to the compact AV node ( N = 5) increased the retrograde ERP and Wenckebach block cycle length by seve...Continue Reading

  • References
  • Citations3

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations3

Citations

Mentioned in this Paper

Biochemical Pathway
Implantable Stimulation Electrodes
Extracellular
Accessory Atrioventricular Bundle
Protoplasm
Left Bundle Branch of His
Hypotrichosis
Aphasia, Broca
Accessory Atrioventricular Bundle (Body Structure)
Chinchilla Rabbits

Related Feeds

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.