Faster pulmonary oxygen uptake kinetics in children vs adults due to enhancements in oxygen delivery and extraction

Scandinavian Journal of Medicine & Science in Sports
Erwan LeclairPatrick Mucci

Abstract

This study aimed to examine if the faster pulmonary oxygen uptake (VO2p) phase 2 in children could be explained by increased O2 availability or extraction at the muscle level. For that purpose, O2 availability and extraction were assessed using deoxyhemoglobin (HHb) estimated by near-infrared spectroscopy during moderate-intensity constant load cycling exercise in children and young adults. Eleven prepubertal boys and 12 men volunteered to participate in the study. They performed one maximal graded exercise to determine the power associated with the gas exchange threshold (GET) and four constant load exercises at 90% of GET. VO2p and HHb were continuously monitored. VO2p , HHb, and estimated capillary blood flow (Qcap) kinetics were modelled after a time delay and characterized by the time to achieve 63% of the amplitude (τ) and by mean response time (MRT: time delay + τ), respectively. Mean values of τ for VO2p (P < 0.001), of MRT for HHb (P < 0.01) and of MRT for Qcap (P < 0.001) were significantly shorter in children. Faster VO2p kinetics have been shown in children; these appear due to both faster O2 extraction and delivery kinetics as indicated by faster HHb and Qcap kinetics, respectively.

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Citations

Feb 21, 2014·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Alan R BarkerNeil Armstrong
Sep 23, 2014·The Journal of Pediatrics·R Lee FrancoRonald K Evans
Apr 13, 2017·Research Quarterly for Exercise and Sport·Neil Armstrong
Nov 23, 2018·Pediatric Exercise Science·Melitta A McNarry
Oct 5, 2013·Medicine and Science in Sports and Exercise·Dan M CooperShlomit Radom-Aizik
Jan 5, 2021·Physiotherapy Theory and Practice·Yann CombretGrégory Reychler
Jul 17, 2021·Journal of Sports Science & Medicine·Bernhard PrinzAlfred Nimmerichter

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