Fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events.

Circulation
Samia MoraPaul M Ridker

Abstract

Although guidelines recommend measuring fasting lipids for initial screening of adults without cardiovascular disease (CVD), recent studies suggest that nonfasting triglycerides may be superior to fasting. Whether fasting status alters associations of nontriglyceride lipids with CVD is unclear. In a prospective study of 26 330 healthy women (19 983 fasting; 6347 nonfasting), associations of baseline lipids with incident CVD (754 fasting; 207 nonfasting) were examined over an 11-year follow-up. Except for triglycerides, lipid concentrations differed minimally (<5%) for fasting versus nonfasting. However, stronger associations with CVD were noted for fasting total cholesterol (adjusted fasting hazard ratio [HR], 1.22 per 1-SD increment; 95% CI, 1.14 to 1.30; nonfasting HR, 1.07; 95% CI, 0.93 to 1.21), low-density lipoprotein (LDL) cholesterol (fasting HR, 1.21; 95% CI, 1.13 to 1.29; nonfasting HR, 1.00; 95% CI, 0.87 to 1.15), apolipoprotein B-100 (fasting HR, 1.36; 95% CI, 1.27 to 1.45; nonfasting HR, 1.20; 95% CI, 1.05 to 1.36), non-high-density lipoprotein (HDL) cholesterol (fasting HR, 1.29; 95% CI, 1.21 to 1.38; nonfasting HR, 1.15; 95% CI, 1.01 to 1.31), and apolipoprotein B-100/A-1 ratio (fasting HR, 1.39; 95% CI, 1.30 to 1...Continue Reading

References

Sep 18, 1996·JAMA : the Journal of the American Medical Association·M J StampferC H Hennekens
Jul 8, 2000·Journal of General Internal Medicine·S R CraigN F Paradise
Nov 13, 2001·The American Journal of Cardiology·E J SchaeferJ J Rubenstein
Nov 12, 2002·Arteriosclerosis, Thrombosis, and Vascular Biology·Philippa J TalmudSteve E Humphries
May 14, 2003·Archives of Internal Medicine·Lynn E EberlyUNKNOWN Multiple Risk Factor Intervention Trial Research Group
Dec 23, 2003·Atherosclerosis·Guy De BackerUNKNOWN Third Joint Force of European and other Societies on Cardiovascular Disease and Prevention in Clinical Practice
Mar 9, 2005·The New England Journal of Medicine·Paul M RidkerJulie E Buring
Jul 7, 2005·JAMA : the Journal of the American Medical Association·Nancy R CookJulie E Buring
Jul 7, 2005·JAMA : the Journal of the American Medical Association·I-Min LeeJulie E Buring
Jul 20, 2007·JAMA : the Journal of the American Medical Association·Børge G NordestgaardAnne Tybjaerg-Hansen
Jul 20, 2007·JAMA : the Journal of the American Medical Association·Sandeep BansalPaul M Ridker
Aug 28, 2007·The American Journal of Cardiology·James H O'Keefe, David S H Bell

❮ Previous
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Citations

Aug 9, 2011·European Journal of Epidemiology·Susanne MoebusKarl-Heinz Jöckel
Apr 29, 2010·Current Diabetes Reports·Byambaa EnkhmaaLars Berglund
Jan 3, 2012·Indian Journal of Clinical Biochemistry : IJCB·P K Nigam
Apr 1, 2010·Journal of Developmental Origins of Health and Disease·C P StewartS K Khatry
Apr 22, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J PepliesUNKNOWN IDEFICS Consortium
Feb 15, 2012·Nature Reviews. Gastroenterology & Hepatology·Paul Moayyedi, Grigorios I Leontiadis
Apr 30, 2009·Metabolic Syndrome and Related Disorders·Frederick J Raal
May 4, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sankar D NavaneethanJoseph V Nally
May 9, 2009·Current Opinion in Cardiology·William B Kannel, Ramachandran S Vasan
Nov 17, 2009·Current Opinion in Lipidology·Sergio LópezFrancisco J G Muriana
May 19, 2012·Current Opinion in Lipidology·Jing PangGerald F Watts
Oct 1, 2010·Diabetes, Obesity & Metabolism·M H Ahmed, C D Byrne
Dec 17, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Richard D Mattes
Sep 24, 2011·International Journal of Vascular Medicine·B KlopManuel Castro Cabezas
Feb 4, 2012·Journal of Nutrigenetics and Nutrigenomics·Roseline Wai Kuan YapMotofumi Masaki
Jun 29, 2012·Thrombosis and Haemostasis·Ida J Hansen-KroneSigrid K Braekkan
Jul 26, 2013·Lipids in Health and Disease·Seungbum ChoiRon Korstanje
Sep 11, 2012·The Journal of Clinical Endocrinology and Metabolism·Lars BerglundUNKNOWN Endocrine society
Jun 1, 2010·Clinical Chemistry·Samia MoraPaul M Ridker
Aug 24, 2013·JMIR Research Protocols·Zainab SamaanUNKNOWN SAHARA Investigators
Mar 24, 2011·Journal of Atherosclerosis and Thrombosis·Shin-Ichiro TanakaMitsuhiro Yokoyama
Apr 30, 2013·Journal of Cardiovascular Computed Tomography·Connie W Tsao, Christopher J O'Donnell
May 26, 2009·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Diana R ChirovskyPhilip Barter
Oct 1, 2011·International Journal of Vascular Medicine·Boudewijn KlopManuel Castro Cabezas
Jan 23, 2014·Lipids in Health and Disease·Martin GruchotUNKNOWN EMIL-Study group
Feb 8, 2014·Annals of Nutrition & Metabolism·Nina E BerentzenHenriëtte A Smit
May 21, 2014·Best Practice & Research. Clinical Endocrinology & Metabolism·Lars BerglundAnton Stalenhoef
Aug 27, 2014·BMC Medicine·Robert H Eckel, Marc-Andre Cornier
Jul 12, 2014·Current Sports Medicine Reports·Benjamin GordonJ Larry Durstine
Jul 12, 2014·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Christian WernerUlrich Laufs

❮ Previous
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