Fasting glycaemia to simplify screening for gestational diabetes

BJOG : an International Journal of Obstetrics and Gynaecology
J Ryser RüetschiM Boulvain

Abstract

Recommendations in Switzerland on screening for gestational diabetes endorse the International Association of Diabetes in Pregnancy Study Group consensus. As universal testing is time consuming and glucose loading is unpleasant, the recommendations include a simplification, not performing the glucose loading in women with fasting glycaemia <4.4 mmol/l. Our objective was to evaluate the diagnostic performance of this simplified strategy, compared with the complete test, in our population with a low prevalence of gestational diabetes. We collected 2298 complete 75-g glucose tolerance tests. We simulated stopping the test, so avoiding the glucose loading and further glycaemia, if fasting glycaemia was <4.4 or ≥5.1 mmol/l. Unselected pregnant women from Geneva and Basel, at 24-28 weeks of gestation. We calculated the sensitivity, and the percentage of women who would avoid the complete test with the strategy based on fasting glycaemia. The prevalence of gestational diabetes was 10.9% in our population. Among 251 women with gestational diabetes, fasting glycaemia was ≥5.1 mmol/l in 119 women (47.4%), between 4.4 and <5.1 mmol/l in 78 women (31.1%) and <4.4 mmol/l in 54 women (21.5%). Proceeding with the complete test only in women w...Continue Reading

References

Mar 1, 1996·Diabetes Care·M L Elks
May 9, 2008·The New England Journal of Medicine·UNKNOWN HAPO Study Cooperative Research GroupDavid A Sacks
Nov 10, 2009·Diabetes Research and Clinical Practice·J E ShawP Z Zimmet
Mar 2, 2010·Diabetes Care·UNKNOWN International Association of Diabetes and Pregnancy Study Groups Consensus PanelMaria Ines Schmidt
Dec 7, 2011·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Mukesh M AgarwalMoshe Hod

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Citations

May 14, 2016·British Journal of Health Psychology·Antje HorschJardena J Puder
Dec 6, 2019·Current Diabetes Reports·Chun-Heng Kuo, Hung-Yuan Li
Aug 1, 2020·Journal of Clinical Medicine·Maria-Christina AntoniouJardena Jacqueline Puder
Dec 29, 2020·Diabetes Research and Clinical Practice·Charlotte NachtergaeleEmmanuel Cosson
Jan 27, 2021·Journal of Clinical Medicine·Charlotte NachtergaeleEmmanuel Cosson
Oct 13, 2021·Clinical Diabetes and Endocrinology·Daria Di FilippoAlec Welsh

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