Fasting status and thermally oxidized sunflower oil ingestion affect the intestinal antioxidant enzyme activity and gene expression of male Wistar rats

Journal of Agricultural and Food Chemistry
Raul Olivero DavidJ Benedí

Abstract

The effect of thermally oxidized sunflower oil ingestion on antioxidant levels, enzyme activities and expressions in the small intestine of fed and fasted rats was studied. For three consecutive days, 12 male Wistar rats received 0.5 g of unused sunflower oil/100 g of body weight (controls, C) while another 12 were given 0.5 g of thermally oxidized sunflower oil/100 g of body weight (test group, T). On the night of day 3, 6 rats from each group were fasted (FC and FT, respectively) while the other 6 animals from each group were given free access to food (NFC and NFT, respectively). On day 4, FC and NFC rats received 1 g of unused oil/100 g of body weight, while FT and NFT rats were given 1 g of altered oil/100 g of body weight. Small intestines were extracted after 4 h exposure to the oils. Fasting and oil alteration significantly interacted modifying total, Se-GPx (both, P < 0.001) and non-Se-GPx (P < 0.05) activity, and GPx and Cu,Zn-SOD expressions (both P < 0.001). FT rats showed a significant increase in TBARS (P < 0.05) and catalase activity (P < 0.001) and a decrease in SOD, Se- and non-Se-dependent GPx activities (at least, P < 0.05) with respect to FC and NFT animals. SOD and GPx expressions decreased (p<0.001) but tha...Continue Reading

References

May 1, 1978·Analytical Biochemistry·M Mihara, M Uchiyama
Jan 1, 1989·Annals of Nutrition & Metabolism·H Yoshida, G Kajimoto
Jan 1, 1984·Methods in Enzymology·H Aebi
Jan 1, 1994·Physiological Reviews·B P Yu
May 1, 1996·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·C K Sen, L Packer
Aug 5, 2000·European Journal of Nutrition·I F Benzie
Nov 1, 2003·The International Journal of Biochemistry & Cell Biology·V M BhorS Sivakami
Jan 2, 2004·Journal of Nutritional Science and Vitaminology·Ya-Yen ChenTsan-Ju Chang
Aug 31, 2004·The British Journal of Nutrition·Carmen Garrido-PolonioFrancisco J Sánchez-Muniz
Jan 13, 2006·Mitochondrion·Karima BegricheBernard Fromenty
Mar 7, 2006·Free Radical Research·M SorensenG Barja
Dec 6, 2006·Pflügers Archiv : European journal of physiology·Elena Thomàs-MoyàAna María Proenza
Jan 12, 2007·Journal of Neuroendocrinology·J Mendoza
Apr 5, 2007·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·R RingseisK Eder
Feb 21, 2009·Molecular and Cellular Biochemistry·Gökhan Sadi, Tülin Güray

❮ Previous
Next ❯

Citations

Aug 25, 2010·Journal of Agricultural and Food Chemistry·Raul Olivero DavidMaría José González-Muñoz
Mar 24, 2011·Journal of Agricultural and Food Chemistry·Raul Olivero-DavidFrancisco José Sánchez-Muniz
Jul 8, 2015·The British Journal of Nutrition·Carmen Dobarganes, Gloria Márquez-Ruiz
Jan 22, 2015·Allergology International : Official Journal of the Japanese Society of Allergology·Hirofumi OginoHitoshi Ueno
Mar 24, 2018·Journal of Basic and Clinical Physiology and Pharmacology·Sunny O AbarikwuChigozie L Onuah
Dec 7, 2018·Biological & Pharmaceutical Bulletin·Atsuhito KubotaKen Iseki
Dec 2, 2020·Journal of the American College of Nutrition·Arunaksharan NarayanankuttyAchuthan C Raghavamenon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.