PMID: 2118636Jul 1, 1990Paper

Fat content and xenobiotic concentrations in human milk: validation of an enzymatic assay of milk fat

Pharmacology & Toxicology
I MathesonJ U Skaare

Abstract

This study reports the validation of an automatic assay for milk triglycerides, as well as the association between milk xenobiotic concentrations and milk triglycerides. The correlation between this assay and a gravimetric reference method for total fat was good (r = 0.997). Triglycerides and xenobiotics were measured in breast milk sampled from one mother. She received two water-soluble drugs, tetracycline and doxycycline in two courses. The levels of organochlorines (DDE, PCB) were also measured and related to those of fat in milk samples from this mother. These and previous results indicate that milk triglyceride variations influence the concentrations of lipophilic xenobiotics in milk.

References

Mar 1, 1978·Bulletin of Environmental Contamination and Toxicology·E M Brevik
Jan 1, 1988·European Journal of Clinical Pharmacology·I Matheson, J Skjaeraasen
Sep 1, 1988·Journal of Pharmaceutical Sciences·H C Atkinson, E J Begg
Jan 1, 1988·European Journal of Clinical Pharmacology·M OstensenH Laufen
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Sep 1, 1984·The American Journal of Clinical Nutrition·M C NevilleP Archer
Jan 23, 1954·British Medical Journal·F E HYTTEN

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Citations

Mar 1, 1995·The American Journal of Clinical Nutrition·M C Neville, C T Walsh
Jul 18, 2018·Basic & Clinical Pharmacology & Toxicology·Johannes J van WattumPeter G J Ter Horst
Jul 24, 2010·Bulletin of Environmental Contamination and Toxicology·Obinna A OjeUchechukwu U Nwodo
Sep 4, 2008·CBE Life Sciences Education·Ian J QuitadamoMartha J Kurtz
Feb 24, 2009·Journal of Dairy Science·G De RosaF Napolitano
Dec 1, 1990·British Journal of Clinical Pharmacology·I MathesonJ E Bredesen

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