PMID: 2500561Jul 1, 1989Paper

Fat emulsion in surgical patients with liver disorders

The Journal of Surgical Research
M NagayamaK Umeyama

Abstract

Total parenteral nutrition (TPN) with fat emulsion was evaluated in 68 patients with liver disorders who were admitted to the First Department of Surgery, Osaka City University Medical School. All patients received transabdominal direct operation for esophageal varices. Immediately after their operations, 28 received TPN with carbohydrate and fat emulsion as an energy source (FAT group), and 40 received TPN with only carbohydrate as an energy source (non-FAT group). Liver function tests, blood glucose levels, intravenous fat tolerance tests, serum lipid levels, fatty acid composition of serum total lipids, and nitrogen balance of the two groups were compared during postoperative TPN. The administration of fat emulsion during postoperative TPN in patients with liver disorders did not worsen the results of liver function tests and the relatively low levels of blood glucose were retained, thereby correcting the abnormalities in the fatty acid composition of serum total lipids. Rates of clearance of fat emulsion during postoperative TPN were significantly higher than in the preoperative period, and changes in serum lipid levels revealed no tendency toward retention of fat emulsion administered intravenously. Nitrogen balance and ch...Continue Reading

References

Dec 1, 1975·Annals of Internal Medicine·M C RiellaB H Scribner
May 1, 1977·Annals of Surgery·J A O'NeillH C Meng
May 1, 1976·Archives of Disease in Childhood·J H PasswellB E Cohen
Aug 1, 1985·The Journal of Surgical Research·M OkunoK Umeyama
Aug 1, 1969·Archives of Internal Medicine·J R Collins, O B Crofford
Aug 1, 1982·Annals of Surgery·J NordenströmJ M Kinney

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Citations

Jan 1, 1994·Journal of Clinical Laboratory Analysis·R K SeraD O Rodgerson
Jan 26, 2010·Metabolism: Clinical and Experimental·Pei-Ra LingBruce R Bistrian
May 18, 2012·The Cochrane Database of Systematic Reviews·Ronald L KoretzTimothy O Lipman

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