Fat Imaging via Magnetic Resonance Imaging (MRI) in Young Children (Ages 1-4 Years) without Sedation

PloS One
Grace E ShearrerJaimie N Davis

Abstract

This pilot study developed techniques to perform Magnetic Resonance Imaging (MRI) of specific fat deposition in 18 children (age 18 months to 4 years). The children engaged in a series of practice tests to become acclimated to the scanner noises, reduce claustrophobia, and rehearse holding still for a set time. The practice tests assessed if the child could remain still for two minutes while watching a video, first while lying on a blanket, second, on the blanket with headphones, and third, in the mock scanner. The children who passed the three practice tests were then scanned with a 3T Siemens Skyra magnet. Abdominal fat distribution (region of interest (ROI) from the top of the ileac crest to the bottom of the ribcage) volume was measured using 2-point DIXON technique. This region was chosen to give an indication of the body composition around the liver. Twelve out of eighteen participants successfully completed the actual MRI scan. Chi-squared test showed no significant difference between male and female pass-fail rates. The median age of completed scans was 36 months, whereas the median age for children unable to complete a scan was 28 months. The average total trunk fat was 240.9±85.2mL and the average total VAT was 37.7±2...Continue Reading

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Citations

Jul 28, 2018·Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community·Eleonora CavarocchiSandro Sorbi
Apr 21, 2019·Journal of Autism and Developmental Disorders·C J SmithJ M Hooker

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sedation
medical procedure

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vibe
MATLAB

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