Fat max as an index of aerobic exercise performance in mice during uphill running

PloS One
Kengo Ishihara, Hirokazu Taniguchi

Abstract

Endurance exercise performance has been used as a representative index in experimental animal models in the field of health sciences, exercise physiology, comparative physiology, food function or nutritional physiology. The objective of the present study was to evaluate the effectiveness of Fatmax (the exercise intensity that elicits maximal fat oxidation) as an additional index of endurance exercise performance that can be measured during running at submaximal exercise intensity in mice. We measured both Fatmax and Vo2 peak of trained ICR mice that voluntary exercised for 8 weeks and compared them with a sedentary group of mice at multiple inclinations of 20, 30, 40, and 50° on a treadmill. The Vo2 at Fatmax of the training group was significantly higher than that of the sedentary group at inclinations of 30 and 40° (P < 0.001). The running speed at Fatmax of the training group was significantly higher than that of the sedentary group at inclinations of 20, 30, and 40° (P < 0.05). Blood lactate levels sharply increased in the sedentary group (7.33 ± 2.58 mM) compared to the training group (3.13 ± 1.00 mM, P < 0.01) when running speeds exceeded the Fatmax of sedentary mice. Vo2 at Fatmax significantly correlated to Vo2 peak, ru...Continue Reading

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Citations

Jan 7, 2020·Journal of Nutritional Science and Vitaminology·Hirokazu TaniguchiKengo Ishihara
Jan 1, 2020·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ana Elisa Speck, Aderbal S Aguiar
Dec 26, 2018·Bioscience, Biotechnology, and Biochemistry·Hirokazu TaniguchiKengo Ishihara

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