Fat necrosis after breast-conserving oncoplastic surgery

Breast Cancer : the Journal of the Japanese Breast Cancer Society
Haruka NakadaHiroshi Nakagomi

Abstract

Fat necrosis is a subjective early as well as delayed complication, which sometimes mimics local recurrence and ruins the quality of life by pain and poor cosmetic result. While, the frequency and severity of fat necrosis are important issues that breast surgeons should explain to the patient, these data are not revealed well. A total of 1476 patients who underwent breast surgery from January 2000 to December 2012 were enrolled in the present study. We assessed fat necrosis by mammographic and physical findings and created grading criteria: Grade (G) 0, no fat necrosis; G1, no symptomatic fat necrosis (mammographic dystrophic calcification); G2, mild symptomatic necrosis (mammographic dystrophic necrosis with tumor); G3, severe symptomatic necrosis (mammographic dystrophic necrosis with pain or skin change); and G4, symptomatic necrosis requiring surgical intervention. Of the 1476 patients enrolled, 393 (27%) underwent mastectomy, and 1083 (73%) underwent breast-conserving surgery. We achieved a high rate of breast-conserving surgery at a total rate of 73% over the study period and maximum rate of 88% in 2010, using oncoplastic procedures. We mainly adopted a pedicled fat flap (417/1083; 39%) and a free dermal fat flap (40/1083...Continue Reading

References

Aug 28, 2002·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Seigo NakamuraKoyu Suzuki
Oct 16, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Bernard FisherUNKNOWN National Surgical Adjuvant Breast and Bowel Project
Jan 20, 2005·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Motohiro TakedaNoriaki Ohuchi
Oct 21, 2005·The New England Journal of Medicine·Edward H RomondNorman Wolmark
Sep 9, 2006·The Breast Journal·Riccardo MasettiFederica Chiesa
Jan 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lawrence J SolinMitchell D Schnall
Apr 24, 2009·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Masakuni Noguchi, Masashi Inokuchi
Oct 23, 2009·Annals of Surgical Oncology·Michelle AzuMonica Morrow
Jun 29, 2011·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Tomoko OgawaYumi Kashikura
Jan 28, 2012·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ashwini BudrukkarRajiv Sarin
Jul 6, 2012·The New England Journal of Medicine·Monica MorrowStuart J Schnitt
Jun 26, 2013·Breast Cancer Research and Treatment·Andrea L Russo, Alphonse G Taghian
Nov 9, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C CriscitielloM Golshan

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Citations

Jun 4, 2020·European Journal of Ophthalmology·Alicia Galindo-FerreiroMohammad Javed Ali
Mar 9, 2019·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Hiroshi NakagomiKoichi Kobayashi
Oct 8, 2020·Current Treatment Options in Oncology·Isis ScomacaoGraham Schwarz
Jan 23, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Shalaka JoshiR A Badwe
Oct 30, 2021·The Cochrane Database of Systematic Reviews·Akriti NandaPankaj G Roy

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