Fat-saturated contrast-enhanced T1-weighted MRI in evaluation of osteosarcoma and Ewing sarcoma

Journal of Magnetic Resonance Imaging : JMRI
S A GronemeyerB D Fletcher

Abstract

To assess contrast-enhanced (C+), fat-saturated (FatSat), T1-weighted (T1W) imaging in the characterization of the soft tissue mass associated with primary bone tumors, we compared it with T2-weighted (T2W) imaging in patients with osteosarcoma (n = 36) and Ewing sarcoma family of tumors (Ewing sarcoma; n = 11). Periosseous tumor compared with normal muscle had greater contrast-to-noise ratio (CNR) on the FatSat T1W C+ image than on T2W for 81% (38/47; P < .0001) of patients. The CNR of periosseous tumor compared with subcutaneous fat was greater on FatSat T1W C+ for 98% (46/47; P < .0001). Radiologists found it easier to evaluate neurovascular bundle proximity to tumor with FatSat T1W C+ images than with T2W for 64% of patients (30/47; P < .0001). They judged FatSat T1W C+ superior to T2W for periosseous tumor conspicuity and visualization of soft tissue necrosis in 62% (29/47; P < .0001). In patients with osteosarcoma or Ewing sarcoma, FatSat T1W C+ imaging may replace T2W imaging for soft tissue mass evaluation, especially if contrast is being used for dynamic enhancement.

References

Jul 1, 1992·AJR. American Journal of Roentgenology·R D TienC S Zee
Feb 1, 1992·AJR. American Journal of Roentgenology·R D Tien
Mar 11, 1991·AJR. American Journal of Roentgenology·J BeltranS Kursunoglu-Brahme
Jan 1, 1990·Magnetic Resonance Imaging·S L HannaB D Fletcher
Sep 1, 1988·AJR. American Journal of Roentgenology·B W DickM Rifkin
Apr 1, 1985·Physics in Medicine and Biology·A HaaseD Matthaei
Oct 1, 1984·Journal of Computer Assisted Tomography·B R RosenT J Brady
Dec 1, 1984·Radiology·K P SoilaP M Starewicz
Jan 1, 1995·Skeletal Radiology·K C LiG H Glover
Nov 1, 1994·American Journal of Otolaryngology·B SinghA R Shaha
Dec 1, 1993·AJR. American Journal of Roentgenology·S A Mirowitz
Jan 1, 1994·AJR. American Journal of Roentgenology·J V Catasca, S A Mirowitz
Mar 1, 1993·Journal of Magnetic Resonance Imaging : JMRI·R C SemelkaM A Kroeker

❮ Previous
Next ❯

Citations

Aug 6, 2000·European Journal of Radiology·K L Verstraete, P Lang
Feb 22, 2002·Critical Reviews in Oncology/hematology·S Burdach, H Jürgens
Jun 13, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·L GorospeP García-Miguel
May 18, 2012·TheScientificWorldJournal·Gandikota GirishDavid Jamadar
May 1, 2012·PM & R : the Journal of Injury, Function, and Rehabilitation·Stephan M Esser, Jennifer Baima
Jan 3, 2012·European Journal of Radiology·C ErraniD Vanel
Sep 27, 2018·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Fangzhou HeWeibin Zhang
Mar 10, 2020·JBJS Reviews·Costantino ErraniAndreas F Mavrogenis
Sep 20, 2020·Journal of Magnetic Resonance Imaging : JMRI·Takatoshi AokiYukunori Korogi
Apr 6, 2004·Journal of Magnetic Resonance Imaging : JMRI·Osamu TokudaNaofumi Matsunaga
Oct 12, 2002·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Seth T WallackWilliam J Hornof
Feb 6, 2020·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·F C F DionísioM H Nogueira-Barbosa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

PM & R : the Journal of Injury, Function, and Rehabilitation
Farah Hameed, Kelly C McInnis
European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie
R BoehmI Joppich
© 2021 Meta ULC. All rights reserved