PMID: 9554560Apr 29, 1998Paper

Fat-soluble vitamins in patients with acute renal failure

Mineral and Electrolyte Metabolism
W DrumlW H Hörl

Abstract

Systematic investigations on the status of fat-soluble vitamins in patients with acute renal failure (ARF) are lacking and hence no recommendations for vitamin supply can be defined for these subjects. Thus we compared the status of fat-soluble vitamins, of transport molecules and some vitamin-dependent proteins in patients with ARF and healthy controls. Nephrology unit of a university hospital. Eight patients with ARF requiring hemodialysis therapy were investigated and 28 healthy volunteers served as controls. Plasma concentrations of retinol (vitamin A) and retinol-binding protein (RBP), 25-OH and 1,25-(OH)2 vitamin D3, of parathyroid hormone (PTH), of alpha-tocopherol (vitamin E) and of phylloquinone (vitamin K), osteocalcin and noncarboxylated osteocalcin, respectively, were measured and plasma lipoprotein fractions (as vitamin transport vehicle) were evaluated. Vitamin A levels were decreased (p < 0.001), but RBP levels were normal in ARF patients. Vitamin D3 metabolites 25-OH and 1,25-(OH)2 vitamin D3 plasma levels were profoundly depressed, and PTH was elevated (p < 0.001). Vitamin E plasma concentration was reduced (p < 0.001) but this cannot be accounted for by decreased LDL cholesterol or triglyceride levels. In cont...Continue Reading

Citations

Aug 1, 2000·Indian Journal of Clinical Biochemistry : IJCB·H LaiS K Aggarwal
Jun 8, 2013·Medizinische Klinik, Intensivmedizin und Notfallmedizin·W Druml
Jul 21, 2009·Current Gastroenterology Reports·Jane M Gervasio, Ann B Cotton
Nov 24, 1999·Kidney International. Supplement·W Druml
Aug 19, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Alejandro PerezJose L Reyes
Dec 22, 2004·Kidney International·Bertrand L JaberVaidyanathapuram S Balakrishnan
Sep 16, 2008·Seminars in Nephrology·Orfeas Liangos, Bertrand L Jaber
Feb 13, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·W Druml
Sep 30, 2005·Hemodialysis International·Jill M Strejc
Nov 30, 2012·Fundamental & Clinical Pharmacology·Dealmy DelgadilloJose L Reyes
Aug 17, 2012·The Cochrane Database of Systematic Reviews·Yi LiTaixiang Wu
Dec 8, 2006·Journal of the American Society of Nephrology : JASN·Mary C PerianayagamBertrand L Jaber
Jun 22, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Sidharth Kumar SethiRupesh Raina
May 23, 2014·Current Opinion in Nephrology and Hypertension·Marta Christov
Dec 10, 2015·Critical Care Medicine·Kai SingbartlJohn A Kellum
Feb 1, 2020·Scientific Reports·Marlies OstermannDanielle E Bear
Nov 6, 2004·Renal Failure·Vladimir GavrilovRafael Gorodischer
Aug 4, 2020·Experimental Biology and Medicine·Chandrashekar AnnamalaiPragasam Viswanathan
Feb 27, 2021·Frontiers in Pediatrics·Anisha HegdeDorey A Glenn
Jan 14, 2005·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Wilfred Druml

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