PMID: 6109152Dec 20, 1980Paper

Fatal disseminated BCG infection in an 18-year-old boy

Lancet
A MackayR G White

Abstract

Death from disseminated infection with BCG (bacille Calmette-Guérin) after routine vaccination is rare, and various immune defects may be responsible. An 18-year-old boy died with widespread lymph-node, bone, lung, and liver involvement 6 years after BCG vaccination. Total numbers of B lymphocytes and T lymphocytes were normal, but T lymphocytes, while transforming normally in the presence of non-specific mitogens, did not transform in the presence of purified protein derivative. Delayed-type hypersensitivity skin tests were negative. Monocytes containing alpha-naphthylacetate esterase were absent.

References

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Citations

Jan 1, 1983·Transactions of the Royal Society of Tropical Medicine and Hygiene·D B Lowrie
Nov 3, 2009·Cancer Biotherapy & Radiopharmaceuticals·Roberto ManfrediEugenio Brunocilla
Nov 1, 1981·Public Health·P Gabb, M O'Brien
May 23, 1987·British Medical Journal·J D Holden
Dec 1, 1983·The Journal of Pathology·M J RidleyD A Willoughby
Jun 1, 1996·Antimicrobial Agents and Chemotherapy·R FrothinghamK N Kreuzer

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