PMID: 8591836Nov 30, 1995Paper

Fatal morphine poisoning in a child due to accidental oral ingestion

Forensic Science International : Synergy
A PoklisD Barron

Abstract

A case of fatal intoxication of an 8 year old child due to accidental oral ingestion of morphine is presented. Following a tonsillectomy and release from the hospital the decedent was prescribed meperidine syrup 50 mg per teaspoon (tsp) to be taken 2 tsps every 4 h. A pharmacist when filling her prescription mistakenly dispensed Roxanol which contained 20 mg/ml morphine sulfate. She took 1 or 2 tsp of the prescription prior to bed and was found dead the next morning. Autopsy findings were unremarkable. Quantitation by gas chromatography/mass spectrometry (GC/MS) yielded the following morphine results: blood, 0.128 mg/l; bile, 135 mg/l and stomach contents, 16 mg/l (2.3 mg total). Based upon the clinical history, autopsy and toxicology finding the cause of death was determined to be poisoning by morphine and the manner of death accidental.

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Citations

Jun 18, 2005·The Journal of Emergency Medicine·Deepak K Sachdeva, John M Stadnyk
May 30, 1998·Acta Anaesthesiologica Scandinavica·D WesterlingG Eklundh
Feb 5, 2016·Forensic Science International : Synergy·María Antonia MartínezJoaquín Garijo
Jan 17, 2016·Forensic Science International : Synergy·F BévalotL Fanton
Feb 18, 2010·Journal of Forensic Sciences·Arne HellandLars Slørdal
Jun 3, 2004·Forensic Science International : Synergy·F MusshoffB Madea
Sep 3, 2010·Tropical Doctor·Nasim ZamaniBabak Mostafazadeh
Jun 11, 2002·Palliative Medicine·L RadbruchK A Lehmann
Jan 5, 2018·Journal of Analytical Toxicology·M SoichotB Delhotal-Landes
Jun 10, 2008·The American Journal of Hospice & Palliative Care·Surjya UpadhyaySushma Bhatnagar
Jun 18, 2019·Drug Testing and Analysis·Raimo A Ketola, Pirkko Kriikku
Jul 7, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Robin E Ferner, Jeffrey K Aronson
Jun 15, 1997·Analytical Chemistry·T A Brettell, R Saferstein

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