PMID: 9547838Apr 21, 1998Paper

Fatal outcome after polytrauma: multiple organ failure or cerebral damage?

Resuscitation
E DereeperJ L Vincent

Abstract

To assess the relative importance of multiple organ failure (MOF) and cerebral damage on the mortality rate following trauma we analyzed retrospectively the records from 99 polytrauma patients admitted to a multidisciplinary European intensive care unit in a 2 year period. In all, 93% of the trauma was non-penetrating and 73% was the result of road accidents. 28 patients died giving an overall mortality of 28.3%. The cause of death was cerebral lesions in 19 patients, hemorrhagic shock in eight and multiple organ failure in one patient who had an injury severity score (ISS) of 13. Most deaths (78%) occurred within 24 h of admission, 15 of these were due to extensive cerebral lesions and seven due to hemorrhagic shock. A total of six deaths occurred after 24 h, four due to extensive cerebral lesions, one due to hemorrhagic shock and one due to multiple organ failure. In our experience, cerebral damage was a more common cause of death than MOF following multiple non-penetrating trauma.

References

Sep 1, 1991·The Journal of Trauma·A FrutigerA Leutenegger
Sep 1, 1990·The American Journal of Emergency Medicine·P Cummings
Nov 1, 1990·The Journal of Trauma·H R ChampionC F Frey
Aug 1, 1986·Archives of Surgery·J K NuytinckP J van Munster
Sep 1, 1983·The Journal of Trauma·E FaistG Heberer
Feb 1, 1982·The Journal of Trauma·R J Goris, J Draaisma
Jul 1, 1980·American Journal of Surgery·C C BakerD D Trunkey
Nov 1, 1995·The American Journal of Emergency Medicine·P ManikisJ L Vincent
May 1, 1996·World Journal of Surgery·G RegelH Tscherne
Jun 23, 2009·Injury·David DewarZsolt Balogh

❮ Previous
Next ❯

Citations

Aug 14, 2002·Indian Journal of Pediatrics·Simmi K RatanJohn Ratan
Nov 24, 2001·Resuscitation·R J HadfieldA R Manara
Mar 25, 2006·Journal of Pediatric Orthopedics·Robert M Kay, David L Skaggs
Jun 19, 2001·Alcoholism, Clinical and Experimental Research·B J ZinkR F Keep
Sep 6, 2007·Critical Care : the Official Journal of the Critical Care Forum·Atle UlvikHans Flaatten
Sep 3, 2011·Journal of Emergencies, Trauma, and Shock·Youichi Yanagawa
Aug 1, 2010·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Heike JakobIngo Marzi
Jun 19, 2007·Injury·Sven LaudiUdo Kaisers
Oct 2, 2020·World Journal of Emergency Surgery : WJES·Johanna M M van BreugelKarlijn J P van Wessem

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.