PMID: 1202183Dec 1, 1975Paper

Fatal outcome in a child with pseudomembranous colitis

Journal of Pediatric Surgery
H J FeeE W Fonkalsrud

Abstract

The clinical and histologic changes occurring with antibiotic-associated pseudomembranous colitis are usually reversible with discontinuation of the causative medication. The spectrum of disease patterns ranges from a benign form to a very fulminant and occasionally fatal one. This report describes a child with a severe form of the disease. Despite recognition and sigmoidoscopic confirmation of this syndrome and cessation of antibiotics, his course continued to deteriorate. Sepsis, leukocytosis, refractory diarrhea, and abdominal distension led to exploratory laparotomy. A proctocolectomy was performed for necrosis of the entire colon; however, the patient died of sepsis.

References

Mar 1, 1960·American Journal of Surgery·C PEARCE, P DINEEN

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Citations

Oct 1, 1995·Diseases of the Colon and Rectum·J L TrudelA N Barkun
Dec 1, 1980·Current Problems in Pediatrics·I Brook
Nov 1, 1990·American Journal of Surgery·J B MorrisT A Stellato
Aug 1, 1981·Australian and New Zealand Journal of Medicine·G J Don, A E Davis

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