Fatal Strongyloides Hyperinfection Syndrome in an Immunocompromised Patient

The American Journal of Case Reports
Vaishnavi PochineniErfidia Restrepo

Abstract

Currently, it is normal to screen for Strongyloides as part of the workup in pre-transplant patients who have eosinophilia. Given the high mortality rates in Strongyloides hyperinfection, this article illustrates the need to screen all patients with eosinophilia who will be started on immunosuppression. We present here an interesting case of a 76-year-old man with membranous glomerulopathy who developed a severe Strongyloides hyperinfection that required an ICU stay and ultimately led to his death a few weeks after initiation of cyclophosphamide and steroids. We recommend that a detailed workup to detect or rule out this parasitic infection be conducted prior to the initiation of immunosuppression in any patient with eosinophilia.

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Citations

Feb 18, 2017·Journal of Parasitology Research·Tiago MendesSilmara Marques Allegretti
Jul 14, 2018·Clinical Reviews in Allergy & Immunology·Vivian C Nanagas, Anna Kovalszki

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Methods Mentioned

BETA
biopsy
ELISA

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