Fate of Extended-Spectrum β-Lactamase-Producing Escherichia coli from Faecal Sources in Surface Water and Probability of Human Exposure through Swimming

Environmental Science & Technology
J F SchijvenAna Maria de Roda Husman

Abstract

The goal of this study was to determine the fate of ESBL-producing Escherichia coli (ESBL-EC) emitted from faecal sources in surface water, and the probability of human exposure through swimming. Concentrations of ESBL-EC were measured in recreational waters and in source waters, being water in ditches surrounding poultry farms and municipal wastewater. Additionally, the potential of ESBL-EC in source waters to reach recreational waters located downstream of these sources was modeled. Modeled ESBL-EC concentrations in recreational waters appeared to be mostly determined by the concentrations in the source waters and by subsequent dilution in surface water, and less by inactivation. The mean (95%) risk of human exposure to ESBL-EC per person per swimming event, as assessed from measured ESBL-EC concentrations in recreational waters, was 0.16 (0.89) for men, 0.13 (0.72) for women and 0.20 (0.95) for children. Similar exposure risks were estimated for hypothetical recreational waters containing 100- or 1000-times diluted source water, located 10 days water travel time downstream of the sources. Human exposure to ESBL-EC through swimming is likely, if recreational waters are located downstream of poultry farms and municipal wastewa...Continue Reading

References

Oct 29, 2000·Risk Analysis : an Official Publication of the Society for Risk Analysis·P F Teunis, A H Havelaar
Feb 23, 2008·The Lancet Infectious Diseases·Johann D D Pitout, Kevin B Laupland
Aug 19, 2008·Applied and Environmental Microbiology·Paul R HunterGary C Barker
Nov 28, 2008·Water Research·P F M TeunisA M de Roda Husman
Jul 15, 2009·International Journal of Antimicrobial Agents·Mark H Wilcox
Mar 5, 2011·Water Research·Franciska M SchetsAna Maria de Roda Husman
Sep 3, 2011·Water Research·Jack F SchijvenAna Maria de Roda Husman
Jul 11, 2013·Environmental Health Perspectives·Nicholas J AshboltEdward Topp
Oct 29, 2013·Applied and Environmental Microbiology·Hetty BlaakFranciska M Schets
May 21, 2014·Environmental Science & Technology·Eelco FranzHetty Blaak

❮ Previous
Next ❯

Citations

Apr 1, 2017·Journal of Water and Health·Susanne WuijtsAna Maria de Roda Husman
Sep 10, 2016·FEMS Microbiology Letters·Benno H Ter KuileStanley Brul
Oct 13, 2018·The Science of the Total Environment·E O'FlahertyE Cummins
Nov 5, 2020·International Journal of Environmental Research and Public Health·Sharon P NappierKaedra R Jones
Nov 6, 2021·Nature Reviews. Microbiology·D G Joakim Larsson, Carl-Fredrik Flach

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.