Fate of left atrial thrombi in patients with atrial fibrillation determined by transesophageal echocardiography and cerebral magnetic resonance imaging

The American Journal of Cardiology
Peter BernhardtHeyder Omran

Abstract

Patients with atrial fibrillation (AF) and atrial thrombi have an increased risk for cerebral embolism. However, there is little knowledge about the long-term fate of atrial thrombi and the incidence of cerebral embolism in patients receiving continued oral anticoagulation. Forty-three consecutive patients with AF and atrial thrombi were enrolled in the study. Serial and prospective transesophageal echocardiographic studies, cranial magnetic resonance imaging (MRI), and clinical examinations were performed during a period of 12 months. Oral anticoagulation was continued or initiated in all patients. An international normalized ratio of 2.0 to 3.0 was regarded as effective. During follow-up, 56% of the thrombi disappeared (7 [16%] at 1 month, 18 [42%] at 3 months, 21 [49%] at 6 months, and 24 [56%] at 12 months). Patients with the disappearance of thrombi had significantly smaller thrombi compared with patients with persistent thrombi (1.5 +/- 0.8 cm in length and 0.8 +/- 0.5 cm in width vs 1.9 +/- 0.6 cm in length and 1.3 +/- 0.4 cm in width, p = 0.04), reduced echogenicity of thrombi (46% vs 89%, p <0.01), and smaller left atrial (LA) volume (83 +/- 27 vs 116 +/- 55 cm(3)). Seven patients (16%) had embolic lesions during follo...Continue Reading

References

Nov 4, 2000·Radiology·P W SchaeferR G Gonzalez
Aug 21, 2001·European Radiology·P LandwehrG Voshage
Sep 12, 2003·The New England Journal of Medicine·Elaine M HylekDaniel E Singer

❮ Previous
Next ❯

Citations

Apr 7, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·P BernhardtH Omran
Jan 26, 2013·Thrombosis and Haemostasis·Christoph HammerstinglGeorg Nickenig
Aug 31, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Bernhard MeierUNKNOWN Document Reviewers
Oct 23, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Hirokazu SadahiroMichiyasu Suzuki
Jun 26, 2015·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Marion FernerThomas Rostock
Jun 24, 2009·Pacing and Clinical Electrophysiology : PACE·Zhao-Xia PuPan-Xiao Hong
Oct 19, 2006·Heart, Lung & Circulation·Constantin B MarcuThomas J Donohue
Sep 13, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Peter BernhardtHeyder Omran
Sep 12, 2016·Journal of Thrombosis and Thrombolysis·Fabio MarsicoPasquale Perrone Filardi
Aug 6, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Michael S WuJim W Cheung
Dec 14, 2011·Stroke; a Journal of Cerebral Circulation·Mark J AlbertsDavid A Garcia
Apr 3, 2020·Rinshō shinkeigaku = Clinical neurology·Mayuko SakuwaHiroki Fukuda
May 10, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Alberto CrestiRaffaele De Caterina
Dec 20, 2012·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Issam JalouliMustapha Ferjani
Apr 29, 2016·European Heart Journal·Giuseppe PattiUNKNOWN Working Group of Thrombosis of the Italian Society of Cardiology
Jul 28, 2020·Archives of Cardiovascular Diseases·Paolo CalabròUNKNOWN Working Group of Interventional Cardiology of the Italian Society of Cardiology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.