Fate of the pancreatic remnant after resection for an intraductal papillary mucinous neoplasm: a longitudinal level II cohort study

Archives of Surgery
Toshiyuki Moriya, William Traverso

Abstract

To determine the occurrence of new disease in the pancreatic remnant after resection for intraductal papillary mucinous neoplasms. A longitudinal level II cohort study. Virginia Mason Medical Center, Seattle, Washington. The primary cohort was a "resection cohort" of 203 patients who underwent partial pancreatic resection for an intraductal papillary mucinous neoplasm. The occurrence rate of lesions in the pancreatic remnant after resection for an intraductal papillary mucinous neoplasm, determined by use of an annual computed tomographic scan of the pancreas. New lesions were observed in the remnant of 17 of the 203 patients (8%) after a median follow-up of 40 months and a median interval of 38 months from the initial resection. Only 1 of these 17 patients with new lesions had a surgical margin that was positive for an adenoma at the time of resection. Comparing the 17 patients with new lesions with the 186 patients without new lesions, we found no difference in age, sex, procedure type, location in ductal system, original histology, or original margin status. In the new lesion group, no treatment was used for 12 patients who had side-branch disease detected by imaging (6% of all patients). Surgical treatment was used for 5 pa...Continue Reading

Citations

May 25, 2013·World Journal of Surgical Oncology·Kun ChengDong-feng Cheng
Jun 26, 2015·North American Journal of Medical Sciences·Norman Oneil MachadoKhalifa Al Wahibi
Jul 21, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·X WangY Zhao
Apr 28, 2017·Scandinavian Journal of Gastroenterology·Linus AronssonDaniel Ansari
Mar 27, 2018·Gut·UNKNOWN European Study Group on Cystic Tumours of the Pancreas
Jun 5, 2018·Annals of Gastroenterological Surgery·Masafumi NakamuraTakao Ohtsuka

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