Fatigue toughness of irradiated vitamin E/UHMWPE blends

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Brinda N DoshiOrhun Kamil Muratoglu

Abstract

Radiation cross-linked ultrahigh molecular weight polyethylenes (UHMWPEs) have become the standard-of-care in total joint replacements (TJR) in the last decade because of their superior wear resistance in comparison with previously used "conventional" gamma sterilized UHMWPE. Some first generation radiation cross-linked UHMWPEs were stabilized against oxidation by post-irradiation melting, which significantly reduced their fatigue crack propagation resistance or fatigue toughness. Second generation cross-linked UHMWPEs incorporated instead an antioxidant such as vitamin E, eliminating the need for melting. In this study, we investigated the fatigue crack propagation resistance and the impact toughness of vitamin E-blended and radiation cross-linked UHMWPEs as a function of vitamin E concentration and radiation dose. Both properties were strongly dependent on the cross-link density and they showed a good correlation with each other (R(2)  = 0.89). © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:1514-1520, 2016.

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Citations

Apr 16, 2016·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ebru OralOrhun K Muratoglu
Dec 13, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Jia-Zhuang XuEbru Oral
Aug 7, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jia-Zhuang XuEbru Oral
Dec 27, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ebru OralOrhun K Muratoglu
Jun 18, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ebru OralOrhun K Muratoglu
May 24, 2020·Radiation and Environmental Biophysics·Naglaa S El-HansiOmar S Desouky
Feb 6, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Barbara H CurrierDouglas W Van Citters
May 14, 2021·JBJS Reviews·Amit ParekhMark Gonzalez

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