Fatty acid carboxylate- and anionic surfactant-controlled delivery systems that use mesoporous silica supports

Chemistry : a European Journal
Carmen CollEliseo Ruiz

Abstract

We report the preparation of a MCM-41 mesoporous material that contains the dye [Ru(bipy)(3)]Cl(2) (bipy=bipyridine) inside the mesopores and functionalised with suitable binding groups at the entrance of the pores. Solids S1-S3 were obtained by the reaction of the mesoporous material with N-methyl-N'-propyltrimethoxysilylimidazolium chloride, N-phenyl-N'-[3-(trimethoxysilyl)propyl]thiourea, or N-phenyl-N'-[3-(trimethoxysilyl)propyl]urea, respectively. A study of the dye delivery of these systems in buffered water (pH 7.0, 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid (HEPES), 10(-3) mol dm(-3)) in the presence of a family of carboxylate ions was carried out. In the interaction of the anions with the surface of the solids, the response depends on the characteristics of the binding groups (i.e., imidazolium, urea and thiourea) at the pore outlets and their specific interaction with the corresponding anion. The interaction of long-chain carboxylate ions with the binding sites at the surface of the solids resulted in a remarkable inhibition of the delivery of the dye. This inhibition was observed clearly for the dodecanoate anion, whereas the octanoate, decanoate, cholate, deoxycholate, glycodeoxycholate and taurocholate...Continue Reading

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Citations

Jan 6, 2016·Chemical Reviews·Elena AznarFélix Sancenón
Mar 17, 2012·Chemistry : a European Journal·Chanhoi KimJyongsik Jang
Oct 23, 2015·ChemistryOpen·Félix SancenónRamón Martínez-Máñez
Dec 12, 2012·Accounts of Chemical Research·Carmen CollFélix Sancenón
Dec 21, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Elena AznarPedro Amorós

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